The J-domain proteins of Arabidopsis thaliana: an unexpectedly large and diverse family of chaperones
AUTOR(ES)
Miernyk, Jan A.
FONTE
Cell Stress Society International
RESUMO
A total of 89 J-domain proteins were identified in the genome of the model flowering plant Arabidopsis thaliana. The deduced amino acid sequences of the J-domain proteins were analyzed for an assortment of structural features and motifs. Based on the results of sequence comparisons and structure and function predictions, 51 distinct families were identified. The families ranged in size from 1 to 6 members. Subcellular localizations of the A thaliana J-domain proteins were predicted; species were found in both the soluble and membrane compartments of all cellular organelles. Based on digital Northern analysis, the J-domain proteins could be separated into groups of low, medium, and moderate expression levels. This genomics-based analysis of the A thaliana J-domain proteins establishes a framework for detailed studies of biological function and specificity. It additionally provides a comprehensive basis for evolutionary comparisons.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=434402Documentos Relacionados
- OWL1: An Arabidopsis J-Domain Protein Involved in Perception of Very Low Light Fluences[W]
- An Auxilin-Like J-Domain Protein, JAC1, Regulates Phototropin-Mediated Chloroplast Movement in Arabidopsis1[w]
- A Cellular J-Domain Protein Modulates Polyprotein Processing and Cytopathogenicity of a Pestivirus
- Role of the J-domain in the cooperation of Hsp40 with Hsp70
- RME-8, a Conserved J-Domain Protein, Is Required for Endocytosis in Caenorhabditis elegans