The Leader Sequence from the 5′-Terminus to the A-Protein Initiation Codon in MS2-Virus RNA
AUTOR(ES)
Wachter, R. De
RESUMO
RNA fragments of different chain length, each containing the 5′-terminal guanosine tetraphosphate (pppGp) of bacteriophage-MS2 RNA, have been isolated from partial ribonuclease digests of the viral RNA. The longest fragment overlaps with the ribosomalbinding site of the A-protein cistron. The base sequence has been established for the major part. The results directly confirm that the A-protein cistron is closest to the 5′-terminus. Its initiating (AUG) codon starts at position 130, being preceded by an untranslated sequence of 129 nucleotides.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=388995Documentos Relacionados
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