The metabolism of circulating maltose in man
AUTOR(ES)
Young, Sister John M.
RESUMO
The utilization of circulating maltose was compared to that of glucose in six normal fasting subjects after intravenous injection of 25 g of either sugar. Blood samples were obtained over a 2 hr period and were assayed for free fatty acids (FFA), insulin, glucose, and total reducing substances. Urine was collected for 2 hr after maltose administration and assayed enzymatically for glucose and maltose. Blood glucose concentrations did not increase after maltose infusion, although a significant rise in total reducing substances was noted, indicating the presence of this disaccharide in the blood. Less than 3% of the administered maltose was excreted in the urine either as maltose or glucose. Initially, there was a fourfold increase in serum insulin concentration after glucose and a threefold increase after maltose infusion. Therefore, serum insulin concentrations gradually declined in a similar manner for both sugars. The plasma FFA at 15 min decreased 371 uEq/liter after glucose and 338 uEq/liter after maltose infusion.