The molecular basis of lung cancer: molecular abnormalities and therapeutic implications
AUTOR(ES)
Massion, Pierre P
FONTE
BioMed Central
RESUMO
Lung cancer is the number one cause of cancer-related death in the western world. Its incidence is highly correlated with cigarette smoking, and about 10% of long-term smokers will eventually be diagnosed with lung cancer, underscoring the need for strengthened anti-tobacco policies. Among the 10% of patients who develop lung cancer without a smoking history, the environmental or inherited causes of lung cancer are usually unclear. There is no validated screening method for lung cancer even in high-risk populations and the overall five-year survival has not changed significantly in the last 20 years. However, major progress has been made in the understanding of the disease and we are beginning to see this knowledge translated into the clinic.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=314397Documentos Relacionados
- Molecular aspects of prostate cancer: implications for future directions
- Gene Mutations in Lung Cancer: Promising Predictive Factors for the Success of Molecular Therapy
- Pathological assessment of mediastinal lymph nodes in lung cancer: implications for non-invasive mediastinal staging.
- Pathological assessment of mediastinal lymph nodes in lung cancer: implications for non-invasive mediastinal staging.
- Pathological assessment of mediastinal lymph nodes in lung cancer: implications for non-invasive mediastinal staging.