The molecular electrostatic potential and steric accessibility of poly (dI.dC). Comparison with poly (dG.dC)
AUTOR(ES)
Lavery, Richard
RESUMO
The influence of the amino group of guanine on the molecular electrostatic potential and the accessibility to reactive sites of B-DNA is investigated by comparing the two model double helices poly (dI.dC) and poly (dG.dC). The calculations clarify the “disruptive” role of the guanine amino group on nucleic acid-polypeptide interactions.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=327660Documentos Relacionados
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