The nifY product of Klebsiella pneumoniae is associated with apodinitrogenase and dissociates upon activation with the iron-molybdenum cofactor.
AUTOR(ES)
Homer, M J
RESUMO
Apodinitrogenase, which lacks the iron-molybdenum cofactor at its active site, is an oligomer that contains an additional protein not found in the active dinitrogenase tetramer. This associated protein in Klebsiella pneumoniae is shown to be the product of the nifY gene. When apodinitrogenase is activated by the addition of the iron-molybdenum cofactor, NifY dissociates from the apodinitrogenase complex. The conditions for this dissociation are described. Finally, there are aspects of the dissociation and insertion process in K. pneumoniae that are different from that in Azotobacter vinelandii.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=204945Documentos Relacionados
- ApoNifH functions in iron–molybdenum cofactor synthesis and apodinitrogenase maturation
- Biosynthesis of the Iron-Molybdenum Cofactor and the Molybdenum Cofactor in Klebsiella pneumoniae: Effect of Sulfur Source
- Biosynthesis of the iron-molybdenum cofactor and the molybdenum cofactor in Klebsiella pneumoniae: effect of sulfur source.
- Iron-molybdenum cofactor synthesis in Azotobacter vinelandii Nif- mutants.
- Synthesis of the iron-molybdenum cofactor of nitrogenase is inhibited by a low-molecular-weight metabolite of Klebsiella pneumoniae.
