The nucleotide sequence at the termini of adenovirus type 5 DNA.
AUTOR(ES)
Steenbergh, P H
RESUMO
The sequences of the first 194 base pairs at both termini of adenovirus type 5 (Ad5) DNA have been determined, using the chemical degradation technique developed by Maxam and Gilbert (Proc. Nat. Acad. Sci. USA 74 (1977), pp. 560-564). The nucleotide sequences 1-75 were confirmed by analysis of labeled RNA transcribed from the terminal HhaI fragments in vitro. The sequence data show that Ad5 DNA has a perfect inverted terminal repetition of 103 base pairs long.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=343247Documentos Relacionados
- Nucleotide sequences at the termini of phi 29 DNA.
- Nucleotide sequence of the transforming early region E1b of adenovirus type 12 DNA: structure and gene organization, and comparison with those of adenovirus type 5 DNA.
- Sequence analysis of the nicks and termini of bacteriophage T5 DNA.
- Nature of the single-stranded DNA in replicating adenovirus type 5 DNA.
- The 3'-terminal nucleotide sequences of adenovirus types 2 and 5 DNA.
