The nucleotide sequences of several tRNA genes from rat mitochondria: common features and relatedness to homologous species.
AUTOR(ES)
Cantatore, P
RESUMO
We have determined the nucleotide sequences of thirteen rat mt tRNA genes. The features of the primary and secondary structures of these tRNAs show that those for Gln, Ser, and f-Met resemble, while those for Lys, Cys, and Trp depart strikingly from the universal type. The remainder are slightly abnormal. Among many mammalian mt DNA sequences, those of mt tRNA genes are highly conserved, thus suggesting for those genes an additional, perhaps regulatory, function. A simple evolutionary relationship between the tRNAs of animal mitochondria and those of eukaryotic cytoplasm, of lower eukaryotic mitochondria or of prokaryotes, is not evident owing to the extreme divergence of the tRNA sequences in the two groups. However, a slightly higher homology does exist between a few animal mt tRNAs and those from prokaryotes or from lower eukaryotic mitochondria.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=320706Documentos Relacionados
- The nucleotide sequence of the large ribosomal RNA gene and the adjacent tRNA genes from rat mitochondria.
- The nucleotide sequences of two tRNA genes from Campylobacter jejuni.
- Nucleotide sequences of nine tRNA genes from Micrococcus luteus.
- PLMItRNA, a database for tRNAs and tRNA genes in plant mitochondria: enlargement and updating
- ARAGORN, a program to detect tRNA genes and tmRNA genes in nucleotide sequences