The P Domain of the P0 Protein of Plasmodium falciparum Protects against Challenge with Malaria Parasites
AUTOR(ES)
Rajeshwari, K.
FONTE
American Society for Microbiology
RESUMO
Monoclonal antibodies (MAbs) specific for the P domain of the Plasmodium falciparum P0 phosphoriboprotein (PfP0) blocked the invasion of RBCs by P. falciparum. Vaccination with this P-domain peptide protected mice upon malaria parasite challenge. The absolute specificity of the MAbs and the PfP0 P peptide makes them potential protective malaria reagents.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=517436Documentos Relacionados
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