The putative sigma factor KatF has a central role in development of starvation-mediated general resistance in Escherichia coli.
AUTOR(ES)
McCann, M P
RESUMO
KatF is required for the expression of some 32 carbon starvation proteins in Escherichia coli including 6 previously identified as Pex. Mutants with the katF gene survive carbon and nitrogen starvation poorly. Many of the KatF-regulated starvation proteins are common to those induced by other stresses, and the mutant failed to develop starvation-mediated cross protection to osmotic, oxidative, and heat stresses. Furthermore, thermal resistance was not induced in the mutant by heat preadaptation, and it exhibited an altered pattern of protein synthesis at elevated temperature. Thus, KatF is a major switch that controls the starvation-mediated resistant state in E. coli.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=208069Documentos Relacionados
- DNA base sequence variability in katF (putative sigma factor) gene of Escherichia coli.
- The putative sigma factor KatF is regulated posttranscriptionally during carbon starvation.
- Nucleotide sequence of katF of Escherichia coli suggests KatF protein is a novel sigma transcription factor.
- Regulation of transcription of katE and katF in Escherichia coli.
- KatF (sigma S) synthesis in Escherichia coli is subject to posttranscriptional regulation.
