The renal tubular handling of aldosterone and its acid-labile conjugate

AUTOR(ES)

Scurry, Murphy T.

RESUMO

Stop-flow studies using infusions of aldosterone-3H or its 3H acid-labile conjugate were done on five rhesus monkeys. The aldosterone-3H urine-to-plasma (U/P) ratio decreased in the same distal urine samples as sodium. The 3H acid-labile conjugate U/P-to-inulin U/P ratio increased in the more proximal samples either with conjugate formed endogenously during aldosterone-3H infusions or with labeled conjugate infused alone. Aldosterone reabsorption occurred at a distal site in the renal tubule, and secretion of its acid-labile conjugate occurred at a proximal site.

Documentos Relacionados

• Presence of an acid-labile alpha-interferon in sera from fetuses and children with congenital rubella.
• The Acid-Labile Subunit Is Required for Full Effects of Exogenous Growth Hormone on Growth and Carbohydrate Metabolism
• SEPARATION FROM TRYPTIC DIGESTS OF CASEIN OF SOME ACID-LABILE COMPONENTS ESSENTIAL IN TETANUS TOXIN FORMATION1
• Endotoxin induction of tumor necrosis factor is enhanced by acid-labile interferon-alpha in acquired immunodeficiency syndrome.
• On the sulfur components of iron-sulfur proteins. I. The number of acid-labile sulfur groups sharing an unpaired electron with iron.