THE ROLE OF INDIVIDUAL SPLEEN CELLS IN THE INTERFERON RESPONSE OF THE INTACT MOUSE*

AUTOR(ES)
RESUMO

A method is described for the detection of interferon production by individual spleen cells of mice after intravenous virus infection. Although mouse spleen plays a major role in the total interferon response to Newcastle disease virus, the number of spleen cells participating is a small fraction of the total, suggesting that interferon formation is to some extent a specialized cell function.

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