The Salmonella typhimurium uracil-sensitive mutation use is in argU and encodes a minor arginine tRNA.

AUTOR(ES)

Lu, C D

RESUMO

The use gene of Salmonella typhimurium was previously identified by a mutation conferring sensitivity to uracil in glucose minimal medium. The use gene was cloned and identified as an allele of argU encoding a tRNA for a minor arginine codon (CGG). The uracil-sensitive phenotype was shown to result from a base substitution in the anticodon stem of this tRNA.

Documentos Relacionados

• Expression of argU, the Escherichia coli gene coding for a rare arginine tRNA.
• The Escherichia coli argU10(Ts) Phenotype Is Caused by a Reduction in the Cellular Level of the argU tRNA for the Rare Codons AGA and AGG
• Frameshift suppression at tandem AGA and AGG codons by cloned tRNA genes: assigning a codon to argU tRNA and T4 tRNA(Arg).
• Characterization of a Salmonella typhimurium hisU mutant defective in tRNA precursor processing.
• Characterization of the cryptic lambdoid prophage DLP12 of Escherichia coli and overlap of the DLP12 integrase gene with the tRNA gene argU.