The Three Dimensional Structure of a Combining Region-Ligand Complex of Immunoglobulin NEW at 3.5-Å Resolution
AUTOR(ES)
Amzel, L. M.
RESUMO
IgG New binds ligands such as orceine, menadione, and uridine with a low affinity (K0 about 1 × 103 liter/mol) and a γ-hydroxy derivative of vitamin K1 with a higher affinity (K0 = 1.7 × 105 liter/mol). Binding studies indicate that both the 2-methylnaphthoquinone rings and the phytyl tail of the vitamin K1 hapten contribute to the total binding energy.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=388242Documentos Relacionados
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