Thermodynamics and dynamics of the formation of spherical lipid vesicles
AUTOR(ES)
Hernández-Zapata, Ernesto
FONTE
Springer Netherlands
RESUMO
We propose a free energy expression accounting for the formation of spherical vesicles from planar lipid membranes and derive a Fokker–Planck equation for the probability distribution describing the dynamics of vesicle formation. We find that formation may occur as an activated process for small membranes and as a transport process for sufficiently large membranes. We give explicit expressions for the transition rates and the characteristic time of vesicle formation in terms of the relevant physical parameters.
ACESSO AO ARTIGO
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