Three-Component Reactions of 7-Hydroxy Coumarin Derivatives, Acetylenic Esters and Aromatic Aldehydes in the Presence of NEt3

AUTOR(ES)

Asghari, Sakineh, Baharfar, Robabeh, Darabi, Samaneh Ahangar, Mohammadian, Reza

FONTE

J. Braz. Chem. Soc.

DATA DE PUBLICAÇÃO

2015-02

RESUMO

Three-component reactions of 7-hydroxy-4-methyl coumarin or 7-hydroxy-4-(trifluoromethyl) coumarin, dialkyl acetylenedicarboxylates and aromatic aldehydes in the presence of NEt3 lead to dialkyl (2E)-2-[aryl(hydroxy)methyl]-3-[(4-methyl-2-oxo-2H-chromen-7-yl)oxy]but-2-ene dioate or dialkyl (2E)-2-[aryl(hydroxy)methyl]-3-{(2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl)oxy} but-2-ene dioate in good yields under mild reaction conditions.

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