Transcription of the Influenza Ribonucleic Acid Genome by a Virion Polymerase III. Completeness of the Transcription Process
AUTOR(ES)
Bishop, David H. L.
RESUMO
The virion ribonucleic acid (RNA) polymerase of influenza strain A0/WS transcribed at least 81% of the viral genome in vitro. The polymerase is shown to be associated with each of the major size classes of the virion RNA-ribonucleoprotein complexes. Under optimal in vitro conditions, at least 45% of the RNA contained in a population of influenza virions was involved in a repetitive transcription process. The detectable proteins associated with enzymatically active complexes containing RNA, ribonucleoprotein, and polymerase have been identified by polyacrylamide gel electrophoresis.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=356522Documentos Relacionados
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