Transfection of an immunoglobulin kappa gene into mature human B lymphocytes.
AUTOR(ES)
Bich-Thuy, L T
RESUMO
We show in this report that the transcription induced by interleukin-2 or pokeweed mitogens of the kappa MOPC 41 immunoglobulin light-chain gene transfected into primary human or murine B lymphocytes initiates from a previously unobserved start site about 26 base pairs upstream of the start site used in myeloma cell lines.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=363164Documentos Relacionados
- Expression of an immunoglobulin heavy chain gene transfected into lymphocytes.
- kappa gene diversity among the clonal progeny of pre-B lymphocytes.
- Enhancer-dependent expression of human kappa immunoglobulin genes introduced into mouse pre-B lymphocytes by electroporation.
- Allelic exclusion in rat kappa immunoglobulin chains: extent of Jk rearrangement in normal B lymphocytes.
- Immunoglobulin heavy chain gene expression in peripheral blood B lymphocytes.
