Transport of an Antifungal Trypsin Inhibitor Isolated from Corn across the Blood-Brain Barrier
AUTOR(ES)
Banks, William A.
FONTE
American Society for Microbiology
RESUMO
We determined whether an antifungal 14-kDa protein trypsin inhibitor isolated from corn is able to cross the blood-brain barrier. We found that it completely crossed the blood-brain barrier by means of a saturable mechanism at a rate of 0.153 μl/g · min, with about 0.082% of the intravenously injected dose being taken up per gram of brain.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=127332Documentos Relacionados
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