Treatment of experimental disseminated candidiasis with cilofungin.
AUTOR(ES)
Perfect, J R
RESUMO
The efficacy of cilofungin treatment of experimental disseminated candidiasis in rabbits was examined. Cilofungin treatment reduced yeast counts, especially in the kidney, with activity comparable to that of amphotericin B. The peak level of cilofungin in serum was measured at 5 min after administration of a single dose, with no drug detectable after 90 min.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=172760Documentos Relacionados
- Efficacy of cilofungin therapy administered by continuous intravenous infusion for experimental disseminated candidiasis in rabbits.
- Treatment of experimental cryptococcal meningitis and disseminated candidiasis with SCH39304.
- Antifungal effects of the nonlinear pharmacokinetics of cilofungin, a 1,3-beta-glucan synthetase inhibitor, during continuous and intermittent intravenous infusions in treatment of experimental disseminated candidiasis.
- Treatment of murine disseminated candidiasis with L-743,872.
- Comparative effects of cilofungin and amphotericin B on experimental murine candidiasis.
