Triparanol Inhibition of Sterol Biosynthesis in Chlorella ellipsoidea12
AUTOR(ES)
Chan, J. T.
RESUMO
The sterol composition of C. ellipsoidea was markedly changed when this alga was grown in the presence of 1 μg/g triparanol. Triparanol appears to inhibit the removal of 14α-methyl group, the second alkylation at C-24, Δ7-reductase, and Δ8 → Δ7-isomerase. The effect of triparanol in Chlorella is much more diversified than the specific effect originally assigned to it in animals.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=366478Documentos Relacionados
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