Truncated Internalin A and Asymptomatic Listeria monocytogenes Carriage: In Vivo Investigation by Allelic Exchange

AUTOR(ES)

Olier, Maïwenn

FONTE

American Society for Microbiology

RESUMO

Allelic exchange of the region coding for the C terminus of InlA between one epidemic (with an 80-kDa InlA) and one asymptomatic (with a 47-kDa InlA) carriage Listeria monocytogenes strain confirmed the need for this region for internalin entry in vitro. Interestingly, restoration of internalin A functionality did not result in full virulence in chicken embryo assays.

Documentos Relacionados

• Expression of Truncated Internalin A Is Involved in Impaired Internalization of Some Listeria monocytogenes Isolates Carried Asymptomatically by Humans
• Identification and purification of novel internalin-related proteins in Listeria monocytogenes and Listeria ivanovii.
• Internalin B promotes the replication of Listeria monocytogenes in mouse hepatocytes.
• The Sortase SrtA of Listeria monocytogenes Is Involved in Processing of Internalin and in Virulence
• Targeting and crossing of the human maternofetal barrier by Listeria monocytogenes: Role of internalin interaction with trophoblast E-cadherin