Tumor necrosis factor does not induce Plasmodium falciparum crisis forms.
AUTOR(ES)
Jensen, J B
RESUMO
Mouse and rabbit sera from animals treated with Mycobacterium bovis BCG and lipopolysaccharide contained tumor necrosis factor (TNF) and induced malaria parasite crisis forms. However, neither purified mouse- nor recombinant DNA-produced human TNF induced crisis forms in cultured Plasmodium falciparum. Furthermore, rabbit polyclonal and mouse monoclonal antibodies against human TNF did not block the parasite inhibitory activity of human malaria crisis form factor serum from Sudan.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=260585Documentos Relacionados
- Plasmodium falciparum varies in its ability to induce tumor necrosis factor.
- Two soluble antigens of Plasmodium falciparum induce tumor necrosis factor release from macrophages.
- Tumor necrosis factor enhances neutrophil-mediated killing of Plasmodium falciparum.
- Human immunodeficiency virus does not induce interleukin-1, interleukin-6, or tumor necrosis factor in mononuclear cells.
- Serological relationship of tumor necrosis factor-inducing exoantigens of Plasmodium falciparum and Plasmodium vivax.
