Two independent pathways of expression lead to self-assembly of the rabbit hemorrhagic disease virus capsid protein.
AUTOR(ES)
Sibilia, M
RESUMO
The rabbit hemorrhagic disease virus capsid protein was expressed in insect cells either as an individual protein species, from a mRNA analogous to the viral subgenomic RNA, or as part of a polyprotein that included the viral 3C-like protease and the RNA polymerase. Both pathways of expression led to the assembly of viruslike particles morphologically and antigenically similar to purified virus.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=189447Documentos Relacionados
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