Two Salmonella OmpC Kb-Restricted Epitopes for CD8+-T-Cell Recognition

AUTOR(ES)

Diaz-Quiñonez, Alberto

FONTE

American Society for Microbiology

RESUMO

We report the identification of two peptides from Salmonella OmpC porin that can bind to major histocompatibility complex class I Kb molecules and are targets of cytotoxic T lymphocytes from Salmonella-infected mice. These peptides are conserved in gram-negative bacterial porins and are the first Salmonella porin-specific epitopes described for possible CD8+-T-cell elimination of infected cells.

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