Tyrosine and Phenylalanine Biosynthesis in Escherichia coli K-12: Complementation Between Different tyrR Alleles
AUTOR(ES)
Im, S. W. K.
RESUMO
Dominance tests in diploids have confirmed that the product of the tyrR gene is involved in a negative control system affecting the synthesis of both 3-deoxy-d-arabinoheptulosonic acid 7-phosphate (DAHP) synthetase (tyr) and DAHP synthetase (phe). Some tyrR mutants are derepressed for the synthesis of both DAHP synthetase (tyr) and (phe), whereas others are derepressed for the synthesis of DAHP synthetase (tyr) but overrepressed for the synthesis of DAHP synthetase (phe). Complementation tests between these alleles confirm that they are in the same cistron. The allele causing overrepression of enzyme synthesis is dominant over both the wild type and the derepressing allele in diploids.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=246364Documentos Relacionados
- Regulation of Tyrosine and Phenylalanine Biosynthesis in Escherichia coli K-12: Properties of the tyrR Gene Product
- Cloning and characterization of Escherichia coli K-12 regulator gene tyrR.
- Regulation of aroL expression by TyrR protein and Trp repressor in Escherichia coli K-12.
- Physical map location and transcriptional orientation of the tyrR gene of Escherichia coli K-12.
- Regulation of expression of the Escherichia coli K-12 mtr gene by TyrR protein and Trp repressor.