Uptake of adenosine and release of adenine derivatives in mammalian non-myelinated nerve fibres at rest and during activity

AUTOR(ES)

Maire, J. C.

RESUMO

1. Influx of adenosine into rabbit non-myelinated nerve fibres was measured using [2-3H]adenosine. The uptake of radioactivity increased linearly with duration of incubation for up to 60 min and adenosine concentration up to 200 μm. The uptake at different adenosine concentrations showed a saturable component with a half-maximal activation at 17·1 μm and a linear part.

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