Urinary Screening Tests to Detect Excessive Lead Absorption*
AUTOR(ES)
Ellis, R. W.
RESUMO
The biological variation encountered in spot urine samples was assessed by collecting six sets of serial urine specimens from five men. The lead, coproporphyrin, and creatinine contents of each specimen were determined and the specific gravity was measured. It is found that as the mean concentration of the metabolite rises so the variability of the individual values increases. The scatter of the concentrations is not significantly different from that found in the rates of excretion. Adjustment of the figures to either a constant specific gravity or creatinine concentration increased the scatter. The effect of the diurnal cycle on the variability is negligible as the spread of the combined results is uniform over the 24-hour period.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1008465Documentos Relacionados
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