Use of diethylenetriamine penta-acetic acid (D.T.P.A.) in the clinical assessment of total body iron stores
AUTOR(ES)
Powell, L. W.
RESUMO
As a quantitative test of iron storage the six-hour urinary excretion of iron was measured after the intravenous infusion of the iron-chelating agent diethylenetriamine penta-acetic acid (D.T.P.A.). The value of this test in determining the presence and magnitude of the total body iron stores was assessed in patients with diseases of iron storage. In patients with idiopathic haemochromatosis and in their first-degree relatives with increased iron stores as measured by hepatic biopsy, the result of the D.T.P.A. test fell progressively as iron stores were reduced by venesection therapy. There was a significant correlation between the result of the D.T.P.A. test and the excess iron storage as measured retrospectively by the effects of venesection therapy, and also between the D.T.P.A. test and the unsaturated iron-binding capacity (U.I.B.C.) in these patients.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=473636Documentos Relacionados
- Diagnostic significance of gadolinium-DTPA (diethylenetriamine penta-acetic acid) enhanced magnetic resonance imaging in thrombolytic treatment for acute myocardial infarction: its potential in assessing reperfusion.
- Etilenodicisteína-99m Tc é um radiofármaco mais efetivo que o ácido dietilenotriaminopentacético-99m Tc para excluir obstrução em pacientes com dilatação das vias urinárias
- Efficacy of treatment with the iron (III) complex of diethylenetriamine pentaacetic acid in mice and primates inoculated with live lethal dose 100 Escherichia coli.
- Difficulties in the Use of Ethylenediamine Tetra-acetic Acid (E.D.T.A.) in Determining Calcium in Serum
- The determination of total body exchangeable O2 stores