Variation in DNA swivel enzyme activity during the mammalian cell cycle.
AUTOR(ES)
Rosenberg, B H
RESUMO
Synchronized cells of a normal human lymphocytic cell line contain little swiven enzyme activity in G0 and G1 and high activity in Sphase. The level of activity in different growth phase appears to be related to the fraction of the population engaged in DNA replication. No endogenous inhibitor or activator of swiven activity could be demonstrated. The evidence implies that the enzyme may be present only during S phase; it is therefore a possible control factor for replication.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=343175Documentos Relacionados
- DNA swivel enzyme activity in a nuclear membrane fraction.
- Gene expression of human DNA polymerase alpha during cell proliferation and the cell cycle.
- Lipid synthesis during the Escherichia coli cell cycle.
- Differential expression of DNA topoisomerases I and II during the eukaryotic cell cycle.
- Coordinated synthesis and degradation of cdc2 in the mammalian cell cycle.