Vi antigen from Salmonella typhosa and immunity against typhoid fever. 11. Safety and antigenicity in humans.
AUTOR(ES)
Levin, D M
RESUMO
Safety and antigenicity of a purified preparation of Salmonella typhosa Vi antigen was evaluated in human volunteers. Dosages of Vi antigen at 25, 50, and 100 mug were less toxic than U.S. standard typhoid vaccine (lot 6A) containing 5 X 10(8) bacteria per dosage. Vi antigen in comparison with the standard typhoid vaccine induced higher hemagglutinating antibody but lower bactericidal antibody responses.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=415434Documentos Relacionados
- Vi Antigen from Salmonella typhosa and Immunity Against Typhoid Fever I. Isolation and Immunologic Properties in Animals
- Detection of urinary Vi antigen as a diagnostic test for typhoid fever.
- Detection of Salmonella typhi D, Vi, and d antigens, by slide coagglutination, in urine from patients with typhoid fever.
- Application of optical properties of the Vi capsular polysaccharide for quantitation of the Vi antigen in vaccines for typhoid fever.
- Immunoblot detection of class-specific humoral immune response to outer membrane proteins isolated from Salmonella typhi in humans with typhoid fever.
