Virulent and Avirulent Encapsulated Variants of Staphylococcus aureus
AUTOR(ES)
Wiley, Bill B.
RESUMO
There are at least two serologically distinct capsular types of coagulase-positive Staphylococcus aureus. Until now, unequivocal evidence for encapsulation of the Smith diffuse variant was lacking. However, the data presented in this paper provide definitive details of encapsulation of the Smith strain. A marked difference in ld50 values for the two serologically distinct capsular types of S. aureus was demonstrated. The paradoxical behavior of these two strains suggested that the host was resistant to one and was susceptible to the other. A survey of the carriage incidence in mice for staphylococci and staphylococcal capsular antibodies disclosed the presence of staphylococci and capsular antibodies in these animals. The capsular antibodies detected were reactive against only one of the capsular types of S. aureus. None of the sera from the mice surveyed possessed capsular antibodies against the Smith diffuse variant, but the average incidence for the capsular antibodies against the wound mucoid type was 46%. We postulated that the susceptibility of the mice to the Smith diffuse variant was caused by the absence of protective, type-specific capsular antibodies. Conversely, the resistance of the mice to the wound mucoid staphylococci may have been a result of the presence of type-specific capsular antibodies.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=252123Documentos Relacionados
- Molecular characterization of plasmids from virulent and spontaneously occurring avirulent colonial variants of Shigella flexneri.
- Chemotaxigenesis by encapsulated Staphylococcus aureus M.
- Biological Properties of the Encapsulated Staphylococcus aureus M
- Chromogenesis by variants of Staphylococcus aureus.
- NONMUCOID MUTANT OF THE ENCAPSULATED SMITH STRAIN OF STAPHYLOCOCCUS AUREUS