Virus of Pekin ducks with structural and biological relatedness to human hepatitis B virus.
AUTOR(ES)
Mason, W S
RESUMO
A virus found in the sera of Pekin ducks appears to be a new member of the human hepatitis B-like family of viruses. This virus had a diameter of 40 nm and an appearance in the electron microscope similar to that of human hepatitis B virus. The DNA genome of the virus was circular and partially single stranded, and an endogenous DNA polymerase associated with the virus was capable of converting the genome to a double-stranded circle with a size of ca. 3,000 base pairs. An analysis for viral DNA in the organs of infected birds indicated preferential localization in the liver, implicating this organ as the site of virus replication. In all of these aspects, the virus bears a striking resemblance to human hepatitis B virus and appears to be a new member of this family, which also includes ground squirrel hepatitis virus and woodchuck hepatitis virus.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=353710Documentos Relacionados
- Viral nucleic acid synthesis and antigen accumulation in pancreas and kidney of Pekin ducks infected with duck hepatitis B virus.
- Cloned duck hepatitis B virus DNA is infectious in Pekin ducks.
- Sequence of events in natural infection of Pekin duck embryos with duck hepatitis B virus.
- Naturally occurring infection of Pekin duck embryos by duck hepatitis B virus.
- Structural relationships between the surface antigens of ground squirrel hepatitis virus and human hepatitis B virus.
