WorfDB: the Caenorhabditis elegans ORFeome Database
AUTOR(ES)
Vaglio, Philippe
FONTE
Oxford University Press
RESUMO
WorfDB (Worm ORFeome DataBase; http://worfdb.dfci.harvard.edu) was created to integrate and disseminate the data from the cloning of complete set of ∼19 000 predicted protein-encoding Open Reading Frames (ORFs) of Caenorhabditis elegans (also referred to as the ‘worm ORFeome’). WorfDB serves as a central data repository enabling the scientific community to search for availability and quality of cloned ORFs. So far, ORF sequence tags (OSTs) obtained for all individual clones have allowed exon structure corrections for ∼3400 ORFs originally predicted by the C. elegans sequencing consortium. In addition, we now have OSTs for ∼4300 predicted genes for which no ESTs were available. The database contains this OST information along with data pertinent to the cloning process. WorfDB could serve as a model database for other metazoan ORFeome cloning projects.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=165539Documentos Relacionados
- Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based RNAi Library
- C. elegans ORFeome Version 3.1: Increasing the Coverage of ORFeome Resources With Improved Gene Predictions
- WormBase as an Integrated Platform for the C. elegans ORFeome
- YPL.db: the Yeast Protein Localization database
- The Yeast Proteome Database (YPD) and Caenorhabditis elegans Proteome Database (WormPD): comprehensive resources for the organization and comparison of model organism protein information
