Astrocyte
Mostrando 1-12 de 180 artigos, teses e dissertações.
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1. Memory impairments and increased GFAP expression in hippocampal astrocytes following hypercaloric diet in rats
RESUMO Objetivo: A inflamação hipotalâmica e a superexpressão da proteína glial fibrilar ácida (GFAP) em astrócitos são bem descritas em animais obesos, assim como déficits cognitivos e de memória. Como o hipocampo desempenha importante papel na consolidação de informações, esta investigação teve como objetivo observar a função da memória
Arq. Neuro-Psiquiatr.. Publicado em: 23/09/2019
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2. Andrographolide protects mouse astrocytes against hypoxia injury by promoting autophagy and S100B expression
Andrographolide (ANDRO) has been studied for its immunomodulation, anti-inflammatory, and neuroprotection effects. Because brain hypoxia is the most common factor of secondary brain injury after traumatic brain injury, we studied the role and possible mechanism of ANDRO in this process using hypoxia-injured astrocytes. Mouse cortical astrocytes C8-D1A (astro
Braz J Med Biol Res. Publicado em: 19/04/2018
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3. PHYTOCHEMICAL ANALYSIS OF HYDROETHANOLIC EXTRACTS FROM POWDERED ROOTS OF Panax ginseng C. A. Meyer AND Heteropterys tomentosa A. Juss AND EVALUATION OF THEIR EFFECTS ON ASTROCYTE CELL DEATH
The medicinal plants Panax ginseng C. A. Meyer (Araliaceae) and Heteropterys tomentosa A. Juss (Malpighiaceae) are widely and separately used by the Brazilian population as phytotherapeutics for the same medicinal purposes as tonics and to improve cognition. A chemical analysis was carried out on hydroethanolic extracts of powdered roots from P. ginseng and
Quím. Nova. Publicado em: 2016-06
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4. A human astrocytoma cell line is highly susceptible to infection with Trypanosoma cruzi
Astrocytes play a vital role in neuronal protection, homeostasis, vascular interchange and the local immune response. Some viruses and parasites can cross the blood-brain barrier and infect glia. Trypanosoma cruzi, the aetiological agent of Chagas disease, can seriously compromise the central nervous system, mainly in immune-suppressed individuals, but also
Mem. Inst. Oswaldo Cruz. Publicado em: 2013-04
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5. Influência da adrenalectomia bilateral nos eventos neurodegenerativos no modelo do parkinsonismo experimental pela 6-OHDA nigral. Enfoque aos mecanismos parácrinos gliais envolvidos na neuroproteção e cicatrização / Text not informed by the author
This study has the objective to evaluate the effect of the bilateral adrenalectomy in the neurodegenerative process and cicatrization on the nigroestriatal pathway injury through 6-hydroxydopamine (6-OHDA) in rat, and in this way contribute for the interpretation of the adreno esteroides hormones effects in the neurodegenerative and neurotrophics process in
Publicado em: 2009
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6. O processo inflamatório, a resposta imune "in situ" e a morte neuronal em sistema nervoso central de pacientes com raiva transmitida por morcegos / Inflammatory process, in situ immune response and neuronal death in central nervous system of patients with rabies transmitted by bats
Viral disease of central nervous system almost invariable fatal, rabies causes about 60.000 deaths yearly, and still remain a neglected disease in most countries, specially in developing ones. We study the meningeal, perivascular and parenquimal environment in central nervous system from patients who dies after bat transmitted rabies, looking for the inflamm
Publicado em: 2009
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7. Influence of Glatiramer acetate on the synaptic stability and glial reaction during the EAE and after motor root avulsion / Influencia do acetato de glatiramer (AG) sobre a estabilidade sinaptica e reação glial durante o curso da EAE e apos avulsão de raizes motoras
Multiple sclerosis (MS) is an inflammatory and demyelinating disease, which etiology is unknown. Although it is the result of a major autoimmune response. The Glatiramer acetate (GA) is a drug used to treat MS and is composed by four peptides homologous to the myelin basic protein (MBP), that is able to reduce the exacerbation and injuries to the CNS. Nevert
Publicado em: 2009
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8. Astrócitos e harmônio da tireóide (T3): desenvolvimento neuronal e neuroproteção
Thyroid hormone (T3) has a significant influence on the development and maturation of the mammalian SNC. T3 modulates neuronal development in an astrocyte-mediated manner, secreting soluble factors and other molecules, as ECM proteins, and regulating neurite outgrowth, neuron proliferation and migration. Astrocytes also participate actively in the neuronal m
Publicado em: 2008
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9. Resposta imune celular em culturas de células do sistema nervoso central de rato infectados com Neospora Caninum.
Neosporosis is a disease caused by Neospora caninum, an intracellular parasite that infects a wide range of animals, causes abortion in cattle, and neurologic disease in dogs. To study the pathogenic effects of this parasite, especially its correlation with the immunological system, we described a model of infection in vitro, using rat glial cells. Glial cel
Publicado em: 2006
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10. Sulfated proteoglycans as modulators of neuronal migration and axonal decussation in the developing midbrain
Proteoglycans are abundant in the developing brain and there is much circumstantial evidence for their roles in directional neuronal movements such as cell body migration and axonal growth. We have developed an in vitro model of astrocyte cultures of the lateral and medial sectors of the embryonic mouse midbrain, that differ in their ability to support neuri
Brazilian Journal of Medical and Biological Research. Publicado em: 2003-08
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11. A direct contact between astrocyte and vitreous body is possible in the rabbit eye due to discontinuities in the basement membrane of the retinal inner limiting membrane
Different from most mammalian species, the optic nerve of the rabbit eye is initially formed inside the retina where myelination of the axons of the ganglion cells starts and vascularization occurs. Astrocytes are confined to these regions. The aforementioned nerve fibers known as medullated nerve fibers form two bundles that may be identified with the naked
Brazilian Journal of Medical and Biological Research. Publicado em: 2003-02
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12. Molecular diversity of astrocytes with implications for neurological disorders
The astrocyte represents the most abundant yet least understood cell type of the CNS. Here, we use a stringent experimental strategy to molecularly define the astrocyte lineage by integrating microarray datasets across several in vitro model systems of astrocyte differentiation, primary astrocyte cultures, and various astrocyterich CNS structures. The inters
National Academy of Sciences.