B Jararacussu
Mostrando 1-12 de 56 artigos, teses e dissertações.
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1. Synthesis and Biological Evaluation of Novel 1,3-Benzoxathiol-2-one Sulfonamides against Toxic Activities of the Venom of Bothrops jararaca and Bothrops jararacussu Snakes
This work describes the synthesis of new 1,3-benzoxathiol-2-one sulfonamides and evaluation of their ability to inhibit some in vitro (coagulant, proteolytic and hemolytic) and in vivo (hemorrhagic, edematogenic and lethality) toxic activities of Bothrops jararaca and Bothrops jararacussu venoms. Compounds have been synthesized from the coupling of intermedi
Journal of the Brazilian Chemical Society. Publicado em: 2022
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2. Anti-ophidian activity of Bredemeyera floribunda Willd. (Polygalaceae) root extract on the local effects induced by Bothrops jararacussu venom
Bredemeyera floribunda roots are popularly used to treat snakebites in the semiarid region of Northeast Brazil, and previous studies indicate the anti-ophidian actions of triterpenoid saponins found in its roots. To assess B. floribunda root extract (BFRE) activity against the effects of Bothrops jararacussu venom (BjuV), antiphospholipasic, antiproteolytic,
Braz J Med Biol Res. Publicado em: 03/12/2018
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3. Pharmacological characterization of cnidarian extracts from the Caribbean Sea: evaluation of anti-snake venom and antitumor properties
Abstract Background: Cnidarians produce toxins, which are composed of different polypeptides that induce pharmacological effects of biotechnological interest, such as antitumor, antiophidic and anti-clotting activities. This study aimed to evaluate toxicological activities and potential as antitumor and antiophidic agents contained in total extracts from fi
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 21/09/2018
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4. Can anti-bothropstoxin-I antibodies discriminate between Bothrops jararaca and Bothrops jararacussu venoms?
Abstract Background Snakes of the genus Bothrops, popularly known as pit vipers, are responsible for most cases of snakebite in Brazil. Within this genus, Bothrops jararacussu and B. jararaca deserve special attention due to the severity of their bites and for inhabiting densely populated areas. Regarding the treatment of snakebites by Bothrops jararacussu
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 27/04/2017
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5. Antitumor potential of the myotoxin BthTX-I from Bothrops jararacussu snake venom: evaluation of cell cycle alterations and death mechanisms induced in tumor cell lines
Abstract Background Phospholipases A 2 (PLA 2 s) are abundant components of snake venoms that have been extensively studied due to their pharmacological and pathophysiological effects on living organisms. This study aimed to assess the antitumor potential of BthTX-I, a basic myotoxic PLA 2isolated from Bothrops jararacussu venom, by evaluating in vitro pro
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 22/12/2015
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6. Bothrops snake venoms and their isolated toxins, an L-amino acid oxidase and a serine protease, modulate human complement system pathways
Background Activation of the complement system plays an important role in the regulation of immune and inflammatory reactions, and contributes to inflammatory responses triggered by envenomation provoked byBothrops snakes. The present study aimed to assess whether Bothrops jararacussuand Bothrops pirajai crude venoms and their isolated toxins, namely serine
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 29/09/2015
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7. Diagnóstico parasitológico e imunológico em fezes de serpentes cativas do Instituto Vital Brazil
Foram analisadas amostras fecais de 56 serpentes do Instituto Vital Brazil, Niterói, Rio de Janeiro, por técnicas de sedimentação e flutuação, para pesquisa de formas evolutivas de parasitos como helmintos e protozoários, e imunoenzimáticas para detecção de antígenos de Cryptosporidium sp. e Giardia sp. Dos animais estudados, 80,3% foram positivos
Rev. Bras. Parasitol. Vet.. Publicado em: 23/05/2014
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8. Seasonal, daily activity, and habitat use by three sympatric pit vipers (Serpentes, Viperidae) from southern Brazil
Serpentes viperídeas são amplamente distribuídas pela América do Sul, com maior radiação ocorrendo na subfamília Crotalinae. Apesar da aparente abundância dessas serpentes ao longo da sua distribuição geográfica, alguns aspectos ecológicos permanecem desconhecidos, principalmente em áreas subtropicais. No presente estudo, avaliamos a atividade (
An. Acad. Bras. Ciênc.. Publicado em: 25/04/2014
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9. Caracterização parcial e avaliação do potencial antibacteriano e antitumoral de uma L-aminoácido oxidase isolada de Bothrops jararacussu / Partial characterization and evaluation of antibacterial and antitumor potential of an L-amino acid oxidase obtained of Bothrops jararacussu
Os venenos de serpentes são misturas ricas em proteínas, enzimas e peptídeos biologicamente ativos, os quais representam aproximadamente 90% dos constituintes totais e, provavelmente, são responsáveis por grande parte dos efeitos biológicos do veneno. A L-aminoácido oxidase (LAAO) é uma das enzimas encontradas nos venenos e muitos são os efeitos atr
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 19/01/2012
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10. Pulsed ultrasound therapy accelerates the recovery of skeletal muscle damage induced by Bothrops jararacussu venom
We studied the effect of pulsed ultrasound therapy (UST) and antibothropic polyvalent antivenom (PAV) on the regeneration of mouse extensor digitorum longus muscle following damage by Bothrops jararacussu venom. Animals (Swiss male and female mice weighing 25.0 ± 5.0 g; 5 animals per group) received a perimuscular injection of venom (1 mg/kg) and treatment
Brazilian Journal of Medical and Biological Research. Publicado em: 2012-06
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11. Aspectos clínico-patológicos do envenenamento botrópico experimental em equinos
Estudou-se as alterações clínico-patológicas e laboratoriais em equinos, inoculados experimentalmente com a peçonha de Bothropoides jararaca, Bothrops jararacussu, Bothrops moojeni e Bothropoides neuwiedi, com a finalidade de fornecer subsídios para o diagnóstico do envenenamento pela picada dessas. Os venenos liofilizados foram diluídos em 1ml de so
Pesquisa Veterinária Brasileira. Publicado em: 2011-09
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12. Envenenamento botrópico em bovinos: tratamento opcional.
Envenenamento botropico em bovinos. Envenenamento por B. alternatus, B. neuwiedi, B. moojeni, B. jararacussu, B. jararaca, B.atrox.
São Carlos. Publicado em: 2011