Balancing Selection
Mostrando 1-12 de 94 artigos, teses e dissertações.
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1. Searching for ancient balanced polymorphisms shared between Neanderthals and Modern Humans
Abstract Hominin evolution is characterized by adaptive solutions often rooted in behavioral and cognitive changes. If balancing selection had an important and long-lasting impact on the evolution of these traits, it can be hypothesized that genes associated with them should carry an excess of shared polymorphisms (trans- SNPs) across recent Homo species. In
Genet. Mol. Biol.. Publicado em: 2018-03
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2. Origins of Bipedalism
ABSTRACT This article aimed to review various theories of bipedalism and provide a holistic answer to human evolution. There have been two questions regarding bipedalism: i) why were the earliest hominins partially bipedal?, and ii) why did hominins become increasingly bipedal over the time and replaced their less bipedal ancestors? To answer these questions
Braz. arch. biol. technol.. Publicado em: 2015-12
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3. Genetic diversity and prevalence of CCR2-CCR5 gene polymorphisms in the Omani population
Polymorphisms in the regulatory region of the CCR5 gene affect protein expression and modulate the progress of HIV-1 disease. Because of this prominent role, variations in this gene have been under differential pressure and their frequencies vary among human populations. The CCR2V64I mutation is tightly linked to certain polymorphisms in the CCR5 gene. The c
Genet. Mol. Biol.. Publicado em: 2014
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4. New evidence for balancing selection at the HLA-G locus in South Amerindians
HLA-G is a non-classical HLA (Human Leukocyte Antigen) molecule characterized by limited tissue distribution under normal physiological conditions and low variability at both DNA and protein levels. Several studies suggest that HLA-G could play a role, as an immunoregulatory molecule, in situations as diverse as transplantation, cancer, viral infections and
Genet. Mol. Biol.. Publicado em: 2012
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5. Um esquema de seleção de rotas para o balanceamento de segurança e desempenho em redes em malha sem fio / Um Esquema de Seleção de Rotas para o Balanceamento de Segurança e Desempenho em Redes em Malha Sem Fio
Wireless mesh networks (WMNs) have been used to support multimedia applications on different domains, such as health care and entertainment, that require high levels of security and performance simultaneously. Those networks comprise of a wireless backbone of routers that cooperate to provide data communication among mobile devices, such as notebooks, PDAs a
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 09/05/2011
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6. Worldwide genetic variation at the 3´-UTR region of the LDLR gene : possible influence of natural selection
The low density lipoprotein receptor gene (LDLR) contains many Alu insertions, and is especially Alu-rich at its 3 -untranslated region (3 -UTR). Previous studies suggested that the LDLR 3 -UTR could regulate gene expression by the stabilization of its mRNA. Given the faster Alu evolutionary rate, and wondering about its consequences in a possibly regulatory
Publicado em: 2011
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7. Uma arquitetura multi-agente de balanceamento de carga para aplicação de objetos distribuídos / A multi-agent load balancing architecture for distribuited object applications
Considering the need for balancing distributed systems, we propose a load balancing service that operates on distributed object applications named MABal. MABal architecture analyses the load levels of nodes and, differently from other load balancing approaches, considers the network transfer during the communication of distributed objects at a use case execu
Publicado em: 2009
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8. Dimorfismo alélico na proteína de superfície MSP-6 de merozoítos de Plasmodium falciparum. / Allelic dimorphism in Plasmodium falciparum merozoite surface protein-6 (MSP-6).
The development of a vaccine against malaria caused by Plasmodium falciparum has been hampered by the high level of antigen polymorphism exhibited by this parasite. Allelic dimorphism is a pattern in which every observed allele of a gene is clearly grouped into one of two families. The dimorphic protein MSP-6 forms a complex with MSP-1 (also dimorphic) on me
Publicado em: 2008
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9. Intentional Sampling / Amostragem intencional
In this work we present the method of intentional sampling by optimization. Such method is based on the fact that we must control the sampling selection whenever we have enough knowledge to guarantee good inferences of known quantities and somehow correlated with those interesting and unknown ones. Linear programming techniques were used to solve the optimiz
Publicado em: 2007
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10. On extending the Hardy-Weinberg law
This paper gives a general mating system for an autosomal locus with two alleles. The population reproduces in discrete and non-overlapping generations. The parental population, the same in both sexes, is arbitrary as is that of the offspring and the gene frequencies of the parents are maintained in the offspring. The system encompasses a number of special c
Genetics and Molecular Biology. Publicado em: 2007
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11. UM PROTOCOLO PARA DESCOBERTA E SELEÇÃO DE RECURSOS EM GRADES MÓVEIS AD HOC / A PROTOCOL FOR RESOURCE DISCOVERY AND SELECTION IN MOBILE AD HOC GRIDS
In the last few years, the use of mobile devices in computational grids has seen a growing interest. Nevertheless, a more challenging issue, the dynamic establishment of mobile grids on wireless ad hoc networks, has been so far only partially addressed. The first contribution of this thesis is the proposal of a software architecture for mobile grids that can
Publicado em: 2007
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12. Balanceamento dinÃmico de jogos: uma abordagem baseada em aprendizagem por reforÃo / Dynamic balancing of games: a boarding based on learning for reinforcement
The entertaining value of digital games depends on issues like graphical interface, story, and gameplay. One of the elements that affect gameplay is the challenge faced by the user, which is defined by game balancing. Balance means to provide adequate challenges, avoiding the extremes of getting the player bored with trivial tasks or becoming frustrated with
Publicado em: 2006