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1. Estudo da produção do antibiótico antitumoral retamicina em biorreatores com células imobilizadas de Streptomyces olindensis ICB20. / Production of the antitumor antibiotic retamycin by immobilized cells of Streptomyces olindensis ICB20 in bioreactors.
The purpose of this study was to investigate the production of the antitumor antibiotic retamycin by immobilized cells of Streptomyces. olindensis ICB20 in bioreactors. Cells were immobilized by entrapment in Ca-alginate gel (3%) after being grown in Erlenmeyers (reactivation and pre-immobilization cultures). The average diameter of the Ca-alginate beads was
Publicado em: 2007