Betamethazone
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1. Determinação do acetato de megestrol em plasma humano por cromatrografia líquida de alta eficiência acoplada ao espectrômetro de massa : aplicação em estudo de bioequivalência / Determination of megestrol acetate in human plasma by high-performance liquid chromatography coupled to mass spectrometry: application to a bioequivalence study
A sensitive and highly selective liquid chromatography-tandem mass spectrometry (LC-MS-MS) method was developed to determine megestrol acetate in human plasma using betamethazone as the internal standard. The analyte and internal standard were extracted from plasma samples by hexane/ethyl acetate (1:1 v/v), and chromatographed on a C18 column. The mobile pha
Publicado em: 2004