Bioassay Liquid Chromatography
Mostrando 1-12 de 87 artigos, teses e dissertações.
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1. Evaluation of recombinant human interferon beta 1b by liquid chromatography methods and bioassay
Recombinant human interferon beta 1b (rhIFNβ-1b) is clinically used to treat multiple sclerosis. A reversed-phase liquid chromatography (RP-LC) method was carried out on a Jupiter C4 column (250 mm × 4.6 mm i.d.). The mobile phase A consisted of 0.1% trifluoroacetic acid (TFA) in water, and the mobile phase B was acetonitrile with 0.1% TFA run at a flow ra
Braz. J. Pharm. Sci.. Publicado em: 24/10/2019
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2. REMOVAL OF TRIBUTYL PHOSPHATE FROM AQUEOUS SOLUTIONS BY TiO2 HETEROGENEOUS PHOTOCATALYSIS SUPPORTED OVER A NEW METAL PLATE WITH KINETIC STUDY
Abstract The aim of this investigation was to study the degradation of tributyl phosphate (TBP) in aqueous solution by heterogeneous photocatalysis (UV-C/TiO2). To perform the investigation, aqueous solutions containing the contaminant were exposed to UV radiation in the absence or presence of TiO2 in suspension or supported on a Fe-Cr metal alloy plate. TBP
Braz. J. Chem. Eng.. Publicado em: 30/09/2019
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3. Identification of Antifungal Compounds from the Root Bark of Cordia anisophylla J.S. Mill.
The dichloromethane extract of the root bark of the Panamanian plant Cordia anisophylla J.S. Mill. (Boraginaceae) presented antifungal activity against a susceptible strain of Candida albicans in a bioautography primary screening. The susceptible strain was used to detect minor active compounds that would not have been detected using a classical approach. In
J. Braz. Chem. Soc.. Publicado em: 2019-03
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4. Antifungal activity of extracts from Atacama Desert fungi againstParacoccidioides brasiliensis and identification ofAspergillus felis as a promising source of natural bioactive compounds
Fungi of the genus Paracoccidioides are responsible for paracoccidioidomycosis. The occurrence of drug toxicity and relapse in this disease justify the development of new antifungal agents. Compounds extracted from fungal extract have showing antifungal activity. Extracts of 78 fungi isolated from rocks of the Atacama Desert were tested in a microdilution as
Mem. Inst. Oswaldo Cruz. Publicado em: 2016-03
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5. Performance characteristics of high performance liquid chromatography, first order derivative UV spectrophotometry and bioassay for fluconazole determination in capsules
The bioassay, first order derivative UV spectrophotometry and chromatographic methods for assaying fluconazole capsules were compared. They have shown great advantages over the earlier published methods. Using the first order derivative, the UV spectrophotometry method does not suffer interference of excipients. Validation parameters such as linearity, preci
Química Nova. Publicado em: 2012
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6. Contaminantes emergentes em água tratada e seus mananciais : sazonalidade, remoção e atividade estrogênica / Emerging contaminants in source and drinking water : seasonalities, removal and estrogenic activity
The purpose of this work was to evaluate an annual profile of both source of supply and drinking water quality in the city of Campinas (São Paulo State) in relation to the presence of caffeine, estrone, 17b-estradiol, estriol, progesterone, testosterone, 17a-ethynylestradiol, mestranol, levonorgestrel, diethylstilbestrol, triclosan, 4-n-octylphenol, 4-n-non
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 22/09/2011
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7. Colonization of Brasilonema octagenarum UFV-E1 (Cyanobacteria) in young plants of eucalyptus and the identification of bioactive substances / Colonização de Brasilonema octagenarum UFV-E1 (Cyanobacteria) sobre plantas jovens de eucalipto e a identificação de substâncias bioativas
Cyanobacteria produces a wide variety of biological compounds of economic-industrial interest, often referred to as "bioactive molecules". This is a broad term that include substances, which at low concentrations, are able to affect vital metabolic processes. Recently, a new species of cyanobacteria, Brasilonema octagenarum UFV-E1, was identified. The cyanob
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/01/2010
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8. ASSESSMENT OF RECOMBINANT HUMAN ERYTHROPOIETIN OF CHROMATOGRAPHIC METHOD VALIDATED AND CORRELATION OF BIOASSAY / AVALIAÇÃO DE ERITROPOIETINA HUMANA RECOMBINANTE POR MÉTODOS CROMATOGRÁFICOS VALIDADOS E CORRELAÇÃO COM O BIOENSAIO
A eritropoietina é uma proteína endógena que estimula a eritropoiese. É clinicamente usada para o tratamento de anemias associadas à falência renal crônica. No presente trabalho foi validado método cromatográfico por exclusão molecular (CL-EM) para a avaliação de potência de eritropoietina humana recombinante (rhEPO) em produtos farmacêuticos,
Publicado em: 2009
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9. CONCEPÇÃO, CONSTRUÇÃO E AVALIAÇÃO DE FOTORREATORES CATALISADOS NA DEGRADAÇÃO DE CARGA POLUENTE E AMOXICILINA EM EFLUENTE HOSPITALAR
The focus of this study was the application of advanced oxidation photoprocesses, heterogeneous photocatalysis and photo-Fenton, in the degradation of pollutant load and amoxicillin in wastewater from the University Hospital of Santa Maria (HUSM), evaluating the photoreactors performance in the degradation efficiency. In the hospital wastewater there is a wi
Publicado em: 2008
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10. DESENVOLVIMENTO E VALIDAÇÃO DE MÉTODO CROMATOGRÁFICO PARA AVALIAÇÃO DE POTÊNCIA DE ERITROPOIETINA HUMANA RECOMBINANTE. CORRELAÇÃO COM O ENSAIO BIOLÓGICO / DEVELOPMENT AND VALIDATION OF CHROMATOGRAPHIC METHOD FOR THE POTENCY ASSESSMENT OF RECOMBINANT HUMAN ERYTHROPOIETIN. CORRELATION WITH THE BIOLOGICAL ASSAY
Erythropoietin is a glycoprotein which stimulates the erythropoiesis, clinically used for the treatment of renal anaemia. The biological and chromatographic methods for the potency evaluation of recombinant human erythropoietin (rhEPO) in pharmaceutical products were validated in the present work. The normocythaemic mice bioassay was carried out in female BA
Publicado em: 2007
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11. Monitoração toxinológica do pescado comercializado nos municípios de São Sebastião e Caraguatatuba, SP / Toxinological monitoring of fisheries comercialized in São Sebastião and Caraguatatuba cities, São Paulo state
The Paralytic Shellfish Poisoning (PSP) toxins are well-known natural bioactive compounds due to their accidental consumption in contaminated seafood. These molecules, of which the most potent representative is saxitoxin (STX), are a class of neurotoxic alkaloids, having different isoforms and varied toxicities, that are produced by some cyanobacteria and so
Publicado em: 2007
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12. Characterization of insecticidal peptides from venom Australian funnel-web spiders
Australian funnel-web spiders are relatively large primitive hunting spiders. Male Atrax robustus spiders have been responsible for a number of human deaths. Venom was collected from the species Hadronyche infensa (Hickman) [female], H. formidabilis [male and female], H. versuta [female], and A. robustus (Cambridge) [male] and was fractionated by high perfor
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2006-04