Biologic Invasion
Mostrando 1-12 de 12 artigos, teses e dissertações.
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1. Invasão de Pinus taeda L. e seus efeitos na comunidade vegetal em campos psamófilos no litoral sul do Brasil / Invasion of Pinus taeda L. in the psammophilous coastal vegetation of southern Brazil
Invasão de Pinus spp. constitui uma importante ameaça em ambientes abertos. Neste trabalho, estudamos padrões espaciais e temporais da invasão de Pinus taeda na vegetação psamófila do Parque Estadual de Itapeva, um dos últimos remanescentes de ecossistemas costeiros no sul do Brasil, e relacionamos a invasão com a estrutura e composição da vegeta�
Publicado em: 2010
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2. AMPA receptors promote perivascular glioma invasion via β1 integrin–dependent adhesion to the extracellular matrix
High-grade gliomas release excitotoxic concentrations of glutamate, which has been shown to enhance tumor proliferation and migration. α-Amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) glutamate receptors are abundantly expressed at the invading edge of glioblastoma specimens, suggesting they may play an important biologic role in tumor invasion.
Duke University Press.
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3. Computerized nuclear morphometry: a new morphologic assessment for advanced gastric adenocarcinoma.
OBJECTIVE: To evaluate the correlation between the morphologic nuclear features and clinicopathologic parameters in patients with advanced gastric cancer. SUMMARY BACKGROUND DATA: Nuclear profiles have been reported as useful prognostic predictors in various cancers. Data from computerized morphometries are objective and quickly derived using conventional mi
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4. Identification of gene function and functional pathways by systemic plasmid-based ribozyme targeting in adult mice
To date, functional genomic studies have been confined to either cell-based assays or germline mutations, using transgenic or knockout animals. However, these approaches are often unable either to recapitulate complex biologic phenotypes, such as tumor metastasis, or to identify the specific genes and functional pathways that produce serious diseases in adul
The National Academy of Sciences.
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5. Functional identification of distinct sets of antitumor activities mediated by the FKBP gene family
Assigning biologic function to the many sequenced but still uncharacterized genes remains the greatest obstacle confronting the human genome project. Differential gene expression profiling routinely detects uncharacterized genes aberrantly expressed in conditions such as cancer but cannot determine which genes are functionally involved in such complex phenot
National Academy of Sciences.
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6. Pathogenesis of Salmonellosis STUDIES OF FLUID SECRETION, MUCOSAL INVASION, AND MORPHOLOGIC REACTION IN THE RABBIT ILEUM
Strains of Salmonella typhimurium were studied in the ligated rabbit ileal loop model to gain insight into the mechanisms whereby bacteria which invade the gastrointestinal mucosa evoke fluid exsorption. The organisms employed differed in various biologic attributes including the ability to invade the ileal epithelium, multiply within the mucosa, elicit an a
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7. Guggulsterone enhances head and neck cancer therapies via inhibition of signal transducer and activator of transcription-3
Treatment of human head and neck squamous cell carcinoma (HNSCC) cell lines with guggulsterone, a widely available, well-tolerated nutraceutical, demonstrated dose-dependent decreases in cell viability with EC50s ranging from 5 to 8 μM. Guggulsterone induced apoptosis and cell cycle arrest, inhibited invasion and enhanced the efficacy of erlotinib, cetuxima
Oxford University Press.
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8. Clinical value of extended biologic staging by bone marrow micrometastases and tumor-associated proteases in gastric cancer.
OBJECTIVE: To investigate whether extended staging, including biologic grading and aspects of an early systemic disease component, would give additional prognostic information on patients with curatively resected gastric cancer. BACKGROUND: Tumor-associated proteolytic mechanisms have been shown to be essential for invasion and metastasis. The urokinase-type
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9. The Ron/STK receptor tyrosine kinase is essential for peri-implantation development in the mouse
The Ron/STK receptor tyrosine kinase is a member of the c-Met family of receptors and is activated by hepatocyte growth factor–like protein (HGFL). Ron activation results in a variety of cellular responses in vitro, such as activation of macrophages, proliferation, migration, and invasion, suggesting a broad biologic role in vivo. Nevertheless, HGFL-defici
American Society for Clinical Investigation.
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10. Plasma CD14 decreases monocyte responses to LPS by transferring cell-bound LPS to plasma lipoproteins
CD14, a myeloid cell-surface receptor and soluble plasma protein, binds LPS and other microbial molecules and initiates the innate immune response to bacterial invasion. The blood concentration of soluble CD14 (sCD14) increases during the systemic response to infection. Although high sCD14 blood levels have correlated with increased risk of dying from severe
American Society for Clinical Investigation.
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11. Polymorphisms in the Chlamydia trachomatis Cytotoxin Locus Associated with Ocular and Genital Isolates
Chlamydia trachomatis is a strict human pathogen producing infections that cause medically important chronic inflammatory diseases, such as blinding trachoma and tubal factor infertility. Isolates exist as serotypes that fall into distinct biologic and pathological groups corresponding to differences in infection tissue tropism and invasion properties. Parad
American Society for Microbiology.
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12. Surgical management and prognostic factors in patients with subungual melanoma.
OBJECTIVE: Forty-six cases of subungual melanoma were reviewed to identify significant clinicopathologic prognostic factors, determine the role of DNA content analysis in the biologic assessment of these tumors, and evaluate the effectiveness of amputation level, lymph node dissection (LND), and regional limb perfusion on the survival of these patients. BACK