Biological Model
Mostrando 1-12 de 1533 artigos, teses e dissertações.
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1. BDNF Val66Met polymorphism and resilience in major depressive disorder: the impact of cognitive psychotherapy
Objective: Clinical and biological correlates of resilience in major depressive disorder are scarce. We aimed to investigate the effect of the Val66Met polymorphism in the BDNF gene on resilience scores in major depressive disorder patients and evaluate the polymorphism’s moderation effect on resilience scores in response to cognitive therapy. Method: A
Braz. J. Psychiatry. Publicado em: 2021-02
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2. Agradecimentos aos Pareceristas ad hoc do volume 18 (ano 2020)
According to the World Health Organization (WHO), Chagas disease (CD), whose etiological agent is the Trypanosoma cruzi (T. cruzi) parasite, affects about eight million people, mainly in Latin America. The cruzain enzyme is highlighted among the main biological targets, since it is the most abundant of the cysteine protease class from T. cruzi and is involve
Trab. educ. saúde. Publicado em: 2021-01
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3. Molecular Modelling Study of Heteroarylamide/Sulfonamide Compounds with Antitrypanosomal Activity
According to the World Health Organization (WHO), Chagas disease (CD), whose etiological agent is the Trypanosoma cruzi (T. cruzi) parasite, affects about eight million people, mainly in Latin America. The cruzain enzyme is highlighted among the main biological targets, since it is the most abundant of the cysteine protease class from T. cruzi and is involve
J. Braz. Chem. Soc.. Publicado em: 2021-01
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4. Medication exposure and predictors of first mood episode in offspring of parents with bipolar disorder: a prospective study
Objectives: To prospectively investigate whether baseline clinical characteristics and medication exposure predict development of major depressive disorder or bipolar disorder in offspring of parents with bipolar disorder. Methods: Youth aged 9-20 years with at least one biological parent with bipolar disorder and no prior history of mood or psychotic epis
Braz. J. Psychiatry. Publicado em: 2020-10
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5. Zn treatment effects on biological potential of fennel bulbs as affected by in vitro digestion process
Abstract Zn treatment effects on the stability of polyphenols, MDA (malondialdehyde) content, antioxidant and lipoxygenase inhibition activities of two varieties of fennel bulbs were studied by using an in vitro gastrointestinal digestion model. Likewise, the effect of Zn on viability cells of E. coli was also performed. The results revealed that high amount
Food Sci. Technol. Publicado em: 2020-06
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6. Crystal Structure and 1H NMR Experimental and Theoretical Study of Conformers of 5-Methyl-1-(4’-methylphenylsulfonylamino)-1H-[1,2,3]-triazole-4-carboxylic Acid Ethyl Ester and 5-Methyl-1-(phenylsulfonylamino)-1H-[1,2,3]-triazole-4-carboxylic Acid Ethyl Ester
We reported experimental and theoretical investigation of conformers of 1,2,3-triazole derivatives, substances of exclusively synthetic origin, subject of extensive studies, because of several biological properties, such as antiviral, antimicrobial and antileishmaniasis. We reported molecular/supramolecular X-ray structures of antiophidian compounds I and II
J. Braz. Chem. Soc.. Publicado em: 2020-05
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7. PHYTOCHEMICAL AND BIOLOGICAL STUDIES OF CONSTITUENTS FROM ROOTS OF Salacia crassifolia (CELASTRACEAE)
Salacia crassifolia traditionally known as “Bacupari-do-Cerrado” is used to treat kidney problems, and as a healing agent for coughs and malaria. The phytochemical study of the S. crassifolia roots led to the isolation of thirteen compounds: abruslactone-A (1), urs-12-ene-3β,25,30-triol (2), carioprystimerin (3), β-sitosterol (4), pristimerin (5), disp
Quím. Nova. Publicado em: 2020-05
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8. PRE- AND PERINATAL FACTORS ASSOCIATED WITH WEIGHT GAIN AMONG PRESCHOOL CHILDREN ENROLLED AT DAY CARE CENTERS
RESUMO Objetivo: Identificar fatores associados com o ganho ponderal excessivo entre pré-escolares de Centros de Educação Infantil (CEIs) em uma capital do Nordeste brasileiro. Métodos: Estudo transversal realizado em cinco CEIs situados no distrito de maior vulnerabilidade socioeconômica do município. Foram incluídas 326 crianças de ambos os sexos
Rev. paul. pediatr.. Publicado em: 13/01/2020
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9. IS THERE A DIFFERENCE BETWEEN RIGHT- VERSUS LEFT-SIDED COLON CANCERS? DOES SIDE MAKE ANY DIFFERENCE IN LONG-TERM FOLLOW-UP?
RESUMO Racional: Desde 1990, foi proposto que a localização distal e proximal do câncer de cólon pode seguir diferentes aspectos biológicos, epidemiológicos, patológicos e prognósticos. Essas diferenças podem ter consequências para o tratamento de pacientes com câncer colorretal. Objetivo: Comparar as características entre pacientes com câncer
ABCD, arq. bras. cir. dig.. Publicado em: 20/12/2019
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10. From yeast to humans: Understanding the biology of DNA Damage Response (DDR) kinases
Abstract The DNA Damage Response (DDR) is a complex network of biological processes that protect cells from accumulating aberrant DNA structures, thereby maintaining genomic stability and, as a consequence, preventing the development of cancer and other diseases. The DDR pathway is coordinated by a signaling cascade mediated by the PI3K-like kinases (PIKK) A
Genet. Mol. Biol.. Publicado em: 13/12/2019
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11. Armadillos and leprosy: from infection to biological model
Rev. Inst. Med. trop. S. Paulo. Publicado em: 25/11/2019
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12. Gestão de eventos QBRN e a utilização do modelo Hysplit: uma revisão integrativa de literatura
RESUMO O potencial risco de exposição das populações aos agentes Químicos, Biológicos, Radioativos e Nucleares (QBRN), seja por causas intencionais ou não, configura-se como questão de segurança nacional e demanda um constante aprimoramento do seu gerenciamento. Os modelos de dispersão atmosférica vêm ganhando destaque como ferramenta de apoio à
Saúde debate. Publicado em: 25/11/2019