Biomolecules Structures
Mostrando 1-12 de 30 artigos, teses e dissertações.
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1. PHENOLIC DERIVATIVES AND ANTIOXIDANT ACTIVITY OF POLAR EXTRACTS FROM Bauhinia pulchella
A tea made with the leaves or stem bark of Bauhinia pulchella Benth (Fabaceae) is used in the treatment of diabetes. Ethanol (EEF) and aqueous (EAF) extracts were obtained from the leaves and the antioxidant and citotoxic activities were tested, as well as quantify the content of flavonoids and phenolic compounds (TPC). EEF and EAF showed similar profiles by
Quím. Nova. Publicado em: 2018-04
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2. Photodynamic therapy of Pythium insidiosum inactivation in vitro and in vivo study / Terapia fotodinâmica para inativação do Pythium insidiosum - estudo in vitro e in vivo
Photodynamic Therapy (PDT) is a therapy based on the interaction of photosensitizer and light, in the presence of oxygen, to induce cellular death. Under the incidence of light, at an appropriated wavelength, these chemical compounds produce reactive oxygen species which affects the biomolecules of the target-cells. Pythiosis is a lifethreatening emerging di
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 02/08/2012
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3. Integrated experimental biophysics and molecular dynamics simulations of biomolecules in solution - the interaction of nuclear receptors with DNA response elements and the inter-domain dynamics of Cellobiohydrolase I / Estudos por modelagem e dinâmica molecular integradas a técnicas físicas para biomoléculas em solução - interação de receptores nucleares a elementos responsivos no DNA e dinâmica inter-domínios da celobiohidrolase I
Collective motions play a fundamental role in solution biomolecule dynamics and energetics. These movements can couple very distant regions in the protein structures affection, for instance, allosteric mechanisms, the establishment of macromolecular complexes, and on the integrated function of multidomain proteins as molecullar machines. In this thesis, we p
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 26/09/2011
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4. Glycolipids from macroalgae: potential biomolecules for marine biotechnology?
Brown, red and green algae from the Southeastern coast of Brazil were successively extracted with chloroform/methanol 2:1 and 1:2 (v/v). The crude lipid extract was partitioned according to Folch and the lower phase enriched in glycolipids was fractionated on a silica gel column chromatography eluted with chloroform, acetone and methanol. Three major orcinol
Revista Brasileira de Farmacognosia. Publicado em: 01/04/2011
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5. Desenvolvimento, caracterizacao e aplicacao da matriz FTO/POLI(3-aminofenol) na deteccao de marcador de lesao cardiaca por fotoluminescencia de quantum dots
The heart is a vital organ propelling blood, that carries oxygen and nutrients throughout the body, but whenever these components do not reach it due to arterial obstruction, there is an electrical instability in the process of contraction of the muscle, causing arrhythmias that often, in less than an hour, causes acute myocardial infarction. The problem and
Publicado em: 2011
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6. SYNTHESIS AND CHARACTERIZATION OF COMPOUNDS FORMED BETWEEN CISPLATINUM AND GLUTATHIONE OR PENICILLAMINE LIGANDS / SÍNTESE E CARACTERIZAÇÃO DE COMPOSTOS FORMADOS ENTRE A CISPLATINA E OS LIGANTES GLUTATIONA OU PENICILAMINA
Cisplatinum is considered an important chemotherapeutic drug used against some kinds of cancer. However, the use of this drug may cause side effects such as ototoxicity, neurotoxicity and, mainly, nephrotoxicity. This fact has been related to the interaction of cisplatinum with biomolecules containing sulfur, such as proteins and amino acids. To promote the
Publicado em: 2010
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7. Study of irradiated bothropstoxin-1 with60Co gamma rays: immune system behavior
Ionizing radiation has been successfully employed to modify the immunological properties of biomolecules. Very promising results were obtained when crude animal venoms, as well as isolated toxins, were treated with 60Co gamma rays, yielding toxoids with good immunogenicity. The achievement of modified antigens with lower toxicity and preserved or improved im
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2009
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8. "Implementação da técnica de correlações angulares perturbadas no laboratório Pelletron para estudo de estruturas e interações de biomoléculas" / Implementation of The Perturbed Angular Correlations Technique at The Pelletron Laboratory for the Study of Biomolecules Structures and Interactions
This work is related to the implementation of a perturbed angular correlation (PAC) spectrometer at the University of São Paulo Pelletron Laboratory. The spectrometer consists of 6 cylindrical BaF$_2$ scintillator detectors, with 3 inches diameter and 6 inches length and a multiparameter CAMAC data acquisition system. Different from usual, the gamma ray ene
Publicado em: 2007
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9. Adducts of 2-desoxiadenosine and 2-desoxicitydine induced of tetrahydrofuran: structural characterization and detection in DNA / Adutos de 2-desoxiadenosina e 2-desoxicitidina induzidos por tetraidrofurano: caracterização estrutural e detecção em DNA
There is a huge concern to identify compounds involved in the development of harmful processes, like cancer. Tetrahydrofuran (THF) is a solvent widely used in industries and recent researches and studies indicated a carcinogenic activity in experimental animals, instigating the investigation of its possible interaction with biomolecules. DNA adducts are used
Publicado em: 2007
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10. Eficencia fotodinamica das protoporfirinas IX de magnesio e zinco
The photodynamic efficiency of protoporphyrin IX (PpIX) and its magnesium (MgPpIX) and zinc (ZnPpIX) derivatives were investigated by comparing the rate of tryptophan (Trp), bovine albumin (BSA) and erythrocytes photoxidation. The solutions of the biomolecules were irradiated with a mercury lamp, for a maximum period of 120 minutes and their photoxidations w
Publicado em: 2003
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11. BSDD: Biomolecules Segment Display Device—a web-based interactive display tool
An interactive web-based display tool, Biomolecules Segment Display Device (BSDD), has been developed to search for and visualize a user-defined motif or fragment among the protein structures available in the Protein Data Bank (PDB). In addition, the tool works for the structures available in a selected sub-set of non-homologous protein structures (25% and 9
Oxford University Press.
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12. Biological inorganic chemistry at the beginning of the 21st century
Advances in bioinorganic chemistry since the 1970s have been driven by three factors: rapid determination of high-resolution structures of proteins and other biomolecules, utilization of powerful spectroscopic tools for studies of both structures and dynamics, and the widespread use of macromolecular engineering to create new biologically relevant structures
The National Academy of Sciences.