Bipolar Disorder And Oxidative Stress
Mostrando 1-7 de 7 artigos, teses e dissertações.
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1. Homocysteine and Psychiatric Disorders
Abstract Psychiatric disorders are highly prevalent all over the world with a great impact on public health. Altered homocysteine metabolism is implicated in the pathogenesis of many of these disorders, as it can interfere in normal methylation of subcellular components, promote neuroexcitotoxicity, and induce oxidative stress and inflammation. There are cum
J. inborn errors metab. screen.. Publicado em: 16/05/2019
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2. Efficacy of adjunctive Garcinia mangostana Linn (mangosteen) pericarp for bipolar depression: study protocol for a proof-of-concept trial
Objective: Bipolar depression is characterized by neurobiological features including perturbed oxidative biology, reduction in antioxidant levels, and a concomitant rise in oxidative stress markers. Bipolar depression manifests systemic inflammation, mitochondrial dysfunction, and changes in brain growth factors. The depressive phase of the disorder is the
Braz. J. Psychiatry.. Publicado em: 11/10/2018
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3. Paraoxonase (PON1) L55M and Q192R polymorphisms in major depression and bipolar affective disorder
Abstract Background Oxidative and nitrosative stress pathways, along with immune-inflammatory response, might play an important role in the pathogenic mechanisms underlying major depression and bipolar disorder. Objective The aim of the present study is to investigate paraoxonase 1 polymorphisms and its correlations with disease parameters in patients wi
Arch. Clin. Psychiatry (São Paulo). Publicado em: 2017-06
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4. Shortened telomere length in bipolar disorder: a comparison of the early and late stages of disease
Objective: Bipolar disorder (BD) has been associated with increased rates of age-related diseases, such as type II diabetes, metabolic syndrome, osteoporosis, and cardiovascular disorders. Several biological findings have been associated with age-related disorders, including increased oxidative stress, inflammation, and telomere shortening. The objective of
Rev. Bras. Psiquiatr.. Publicado em: 17/10/2016
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5. Oxidative stress markers, cognitive functions, and psychosocial functioning in bipolar disorder: an empirical cross-sectional study
Objective: This study aimed to evaluate the relationship between oxidative stress markers and cognitive functions and domains of psychosocial functioning in bipolar disorder. Methods: Oxidative stress markers, cognitive functions, and domains of psychosocial functioning were evaluated in 51 patients with bipolar disorder who were in remission. Correlation a
Rev. Bras. Psiquiatr.. Publicado em: 25/04/2014
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6. Staging and neuroprogression in bipolar disorder: a systematic review of the literature
INTRODUCTION: The use of clinical staging models is emerging as a novel and useful paradigm for diagnosing severe mental disorders. The term "neuroprogression" has been used to define the pathological reorganization of the central nervous system along the course of severe mental disorders. In bipolar disorder (BD), neural substrate reactivity is changed by r
Rev. Bras. Psiquiatr.. Publicado em: 2013-03
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7. INFLUENCE DIFFERENT FATTY ACID OF THE DIET ON AN ANIMAL MODEL OF MANIA INDUCED BY AMPHETAMINE IN RATS / INFLUÊNCIA DOS DIFERENTES ÁCIDOS GRAXOS DA DIETA SOBRE UM MODELO ANIMAL DE MANIA INDUZIDO POR ANFETAMINA EM RATOS
Fatty acids (FA) are constituent important of the neuronal phospholipids membranes and they carry out important functions in the development and function of the brain During the last decades changes were observed in the feeding habits of western countries, with an increase of the trans FA and omega-6 (n-6) and detriment of omega-3 fatty acids (n-3) consumpti
Publicado em: 2010