Blocking Antibodies
Mostrando 1-12 de 534 artigos, teses e dissertações.
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1. Recombinant hepatitis C virus-envelope protein 2 interactions with low-density lipoprotein/CD81 receptors
Hepatitis C virus (HCV) envelope protein 2 (E2) is involved in viral binding to host cells. The aim of this work was to produce recombinant E2B and E2Y HCV proteins in Escherichia coli and Pichia pastoris, respectively, and to study their interactions with low-density lipoprotein receptor (LDLr) and CD81 in human umbilical vein endothelial cells (HUVEC) and
Mem. Inst. Oswaldo Cruz. Publicado em: 26/05/2015
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2. Effects of blocking αvβ3 integrin by a recombinant RGD disintegrin on remodeling of wound healing after induction of incisional hernia in rats
PURPOSE: To investigate the changes induced by DisBa-01 on repair of wound healing after induced incisional hernia (IH) in rats. METHODS: Thirty two male albino rats were submitted to IH and divided into four experimental groups: G1, placebo control; G2, DisBa-01-treated; G3, anti-αvβ3 antibodies-treated and G4, anti-α2 antibodies-treated. Histological,
Acta Cir. Bras.. Publicado em: 2015-02
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3. Effects of Blocking αvβ3 integrin by a recombinant RGD disintegrin on remodeling of wound healing after induction of incisional hernia in rats
PURPOSE: Incisional hernia (IH) is characterized by defective wound healing process. Disba-01, a αvb3 integrin blocker has shown to control the rate of wound repair and therefore it could be a target for new wound healing therapies.The objective of the study was to determine the changes induced by Disba-01 on repair of wound healing after induced IH in rat
Acta Cir. Bras.. Publicado em: 2014
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4. Serological detection of West Nile virus in horses and chicken from Pantanal, Brazil
In an effort to detect West Nile virus (WNV) in Brazil, we sampled serum from horses and chickens from the Pantanal region of the state of Mato Grosso and tested for flavivirus-reactive antibodies by blocking ELISA. The positive samples were further confirmed for serological evidence of WNV infection in three (8%) of the 38 horses and one (3.2%) of the 31 ch
Mem. Inst. Oswaldo Cruz. Publicado em: 2012-12
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5. Fatores associados à Infecção pelo vírus da diarreia viral bovina e pelo Herpesvírus Bovino tipo 1 em rebanhos leiteiros da Mesorregião Centro-Oriental do Rio Grande do Sul
The dairy cattle is important to supply the Brazilian market, with the state of Rio Grande do Sul as the second largest producer. Viral diseases cause several damages in the bovine production. In order to maintain and improve the level of production, it becomes important to establish health programs that allow the control of diseases that can result in large
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2012
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6. Biossegurança no controle da infecção hospitalar: desenvolvimento de imunossensor impedimétrico para detecção de Staphylococcus aureus em áreas críticas hospitalares / Biosafety in the control of hospital infection: development of an impedimetric immunosensor for detection of Staphylococcus aureus in critical areas of hospitals
The Biosafety is a very important tool for the Control of Hospital Infection establishing through methods, techniques and standards, measures to be adopted in order to prevent and control risks that may contribute to hospital infection. This work reports the development of an impedimetric immunosensor for detection of pathogenic bacteria, specifically Staphy
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 21/10/2011
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7. Participação das selectinas nas interações entre células angiogênicas da medula óssea e endotélio de músculos isquêmicos de membros inferiores em modelo murino.
The stimulation of vascular growth by angiogenic stem cells transplantation is a promising alternative for the treatment of PAD. Adhesive mechanisms governing progenitor/stem cell trafficking through the microcirculation of ischemic muscles are broadly unknown. The aim of this work was to evaluate the involvement of selectins on interactions between transpla
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/05/2011
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8. Malaria transmission blocking immunity and sexual stage vaccines for interrupting malaria transmission in Latin America
Malaria is a vector-borne disease that is considered to be one of the most serious public health problems due to its high global mortality and morbidity rates. Although multiple strategies for controlling malaria have been used, many have had limited impact due to the appearance and rapid dissemination of mosquito resistance to insecticides, parasite resista
Memórias do Instituto Oswaldo Cruz. Publicado em: 2011-08
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9. Neutralising antibodies for West Nile virus in horses from Brazilian Pantanal
Despite evidence of West Nile virus (WNV) activity in Colombia, Venezuela and Argentina, this virus has not been reported in most South American countries. In February 2009, we commenced an investigation for WNV in mosquitoes, horses and caimans from the Pantanal, Central-West Brazil. The sera of 168 horses and 30 caimans were initially tested using a flaviv
Memórias do Instituto Oswaldo Cruz. Publicado em: 2011-06
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10. Expression and possible functional role of galectin-3 in the / Expressão e possível papel funcional da galectina-3 no timo de camundongos diabéticos não-obesos (NOD)
Galectin-3 belongs to a family of endogenous lectins which bind to -galactosides presented on the cell surface and extracellular matrix glycoproteins. It is involved in multiple biological functions such as cell growth, adhesion, proliferation and apoptosis. Moreover, galectin-3 is found in several tissues and organs, being highly conserved among animal spec
Publicado em: 2010
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11. Estudo dos efeitos biológicos de uma desintegrina recombinante do veneno da serpente Bothrops alternatus, DisBa-01, sobre a musculatura da parede abdominal após indução de hérnia incisional em ratos
INTRODUCTION: The incisional hernia (IH) is one of the most frequent complications after laparotomy, causing high rates of re-operations. Advances in suture material, in the guidelines for incisions, in the techniques of closure and use of dentures (screens), have failed in the elimination of this surgical complication. In this context, advances in the under
Publicado em: 2009
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12. Use of biotech manipulation of oocytes enclosed in preantral follicles for in vitro evaluation of potential anti-zona pellucida to imunoesterilização bitches. / Utilização da biotécnica de manipulação de oócitos inclusos em folículos pré-antrais para a avaliação in vitro do potencial de anticorpos anti-zona pelúcida para a imunoesterilização de cadelas.
The aim of this study was do evaluate the potential of anti-zona pellucida antibodies for immunosterilization in dogs, through analyzing the capability of anti-porcine zona pellucida (pZP) antibodies to cause atresia of preantral follicles (PF). For this purpose, the biotechnique of manipulation of oocytes enclosed in preantral follicles was employed to esta
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 22/12/2008