Borano
Mostrando 1-7 de 7 artigos, teses e dissertações.
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1. Electrochemical behavior of hexamethylbenzene isocloso ruthenium-borane complex at a glassy carbon electrode in non-aqueous medium
O comportamento eletroquímico do complexo rutênio-borano [(C6Me6)-isocloso-1-RuB9 H9] foi investigado utilizando um eletrodo de carbono vítreo em 0,1 mol L-1 de perclorato de tetrabutil amônio dissolvido em cloreto de metileno, utilizando um intervalo de temperatura entre -20 ºC < T < 21 ºC. Utilizaram-se técnicas de voltametria cíclica convolutiva,
Journal of the Brazilian Chemical Society. Publicado em: 2010
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2. Novel Tc-99m radiotracers for brain imaging
Uma nova classe de complexos de Tc-99m capazes de atravessar a barreira hemato-encefálica foi investigada e descrita neste trabalho. Estes compostos são formados reagindo os precursores bissubstituídos do nitrido [99mTc(N)(PS)2] (PS = phosphino-tiol ligante) com trietillborano (BEt3) sob restritas condições anidras e usando solventes não aquosos. A est
Brazilian Archives of Biology and Technology. Publicado em: 2007-09
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3. Estudo teorico sobre os momentos dipolares de metilaminas, fosfinas, seus adultos com borano e sobre formação dos adultos entre fosfinas e borano
Esta tese consiste de duas partes. A primeira se refere a uma análise teórica semi-empírica das tendências não usuais dos momentos dipolares como função da substituição metila para quatro séries de moléculas relacionadas: (CH3)xH3-xE e (CH3)xH3-xE:BH3, onde E é nitrogênio ou fósforo e x=03. Os momentos dipolares são avaliados usando os método
Publicado em: 1974
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4. Boron-containing aptamers to ATP
Boron neutron capture therapy (BNCT), an experimental treatment for certain cancers, destroys only cells near the boron; however, there is a need to develop highly specific delivery agents. As nucleic acid aptamers recognize specific molecular targets, we investigated the influence of boronated nucleotide analogs on RNA function and on the systematic evoluti
Oxford University Press.
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5. Structural basis for activation of α-boranophosphate nucleotide analogues targeting drug-resistant reverse transcriptase
AIDS chemotherapy is limited by inadequate intracellular concentrations of the active triphosphate form of nucleoside analogues, leading to incomplete inhibition of viral replication and the appearance of drug-resistant virus. Drug activation by nucleoside diphosphate kinase and inhibition of HIV-1 reverse transcriptase were studied comparatively. We synthes
Oxford University Press.
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6. Synthesis of 5-substituted 2'-deoxycytidine 5'-(alpha-P-borano)triphosphates, their incorporationinto DNA and effects on exonuclease.
Direct PCR sequencing with boronated nucleotides provides an alternative to current PCR sequencing methods. The positions of boranophosphate-modified nucleotides incorporated randomly into DNA during PCR can be revealed directly by exonuclease digestion to give sequencing ladders. Cytosine nucleotides, however, are especially sensitive to exonuclease digesti
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7. Direct PCR sequencing with boronated nucleotides.
A method is described to simultaneously amplify and sequence DNA using a new class of nucleotides containing boron. During the polymerase chain reaction, boron-modified nucleotides, i.e. 2'-deoxynucleoside 5'-alpha-[P-borano]-triphosphates, are incorporated into the product DNA. The boranophosphate linkages are resistant to nucleases and thus the positions o