Butyrolactones
Mostrando 1-6 de 6 artigos, teses e dissertações.
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1. Butyrolactones from the Endophytic Fungus Aspergillus versicolor and their Anti-Tobacco Mosaic Virus Activity
New butyrolactones aspernolides C and D, along with two known butyrolactones (A and B) were isolated from the culture of the endophytic fungus Aspergillus versicolor. Their structures were elucidated on the basis of extensive spectroscopic analysis, including 1D and 2D nuclear magnetic ressonance techniques, and electronic circular dichroism. The butyrolacto
J. Braz. Chem. Soc.. Publicado em: 2015-03
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2. Diastereoselective synthesis of β-piperonyl-γ-butyrolactones from morita-baylis-hillman adducts. highly efficient synthesis of (±)-yatein, (±)-podorhizol and (±)-epi-podorhizol
Descrevemos nesse trabalho um método simples e eficiente para a preparação diastereosseletiva de b-piperonil-g-butirolactonas hidroxiladas, a partir de um aduto de Morita-Baylis-Hillman. Para exemplificar a eficiência dessa abordagem descrevemos também as sínteses das lignanas biologicamente ativas, (±)-yateína, (±)-podorizol e (±)-epi-podorizol.
Journal of the Brazilian Chemical Society. Publicado em: 2010-12
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3. Study about the synthesis of autoregulators butyrolactones of the Streptomyces bacteria. / Estudos sobre a síntese de butirolactonas auto-reguladoras de bactérias Streptomyces.
Streptomycetes are Gram-positive filamentous bacteria well known for the ability to produce a wide variety of secondary metabolites and biologically active substances. These activities are controlled by low-molecular-weight compounds called butyrolactone autoregulators. The greater number of these compounds with autoregulators properties have as common chara
Publicado em: 2007
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4. Application of biocatalysis in the enantioselective synthesis of chiral gamma-butyrolactones: new reagents for the stereoselective preparation of analogous of vitamin A / Aplicação da biocatálise na síntese de γ-butirolactonas bioativas quirais: novos reagentes visando a preparação estereosseletiva de análogos da vitamina A
The first chapter of this thesis is dedicated to the studies on the application of biocatalysis in the synthesis of chiral γ-butyrolactones. We started investigating the preparation of phenylselanyl-γ-butyrolactones through the kinetic enzymatic resolution of the corresponding phenylselanyl-γ-hydroxyesters. By using this strategy both enantiom
Publicado em: 2005
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5. Streptomyces-derived quorum-sensing systems engineered for adjustable transgene expression in mammalian cells and mice
Prokaryotic transcriptional regulatory elements have been adopted for controlled expression of cloned genes in mammalian cells and animals, the cornerstone for gene-function correlations, drug discovery, biopharmaceutical manufacturing as well as advanced gene therapy and tissue engineering. Many prokaryotes have evolved specific molecular communication syst
Oxford University Press.
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6. Multiple mechanisms of picrotoxin block of GABA-induced currents in rat hippocampal neurons.
1. We have examined the effect of picrotoxin on GABA-induced currents in dissociated rat hippocampal neurons. In addition, we used the putative picrotoxin receptor antagonist, alpha-isopropyl-alpha-methyl-gamma-butyrolactone (alpha IMGBL), and the picrotoxin agonist, beta-ethyl-beta-methyl-gamma-butyrolactone (beta EMGBL) to explore the mechanisms of picroto