C Terminus S100a9
Mostrando 1-7 de 7 artigos, teses e dissertações.
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1. Evaluation of possible mechanisms involved in the antinociceptive effect of the C-terminus of murine S100A9 on experimental neuropathic pain: an experimental approach / Avaliação de possíveis mecanismos envolvidos no efeito antinociceptivo do C-terminal da S100A9 murina sobre a dor neuropática experimental
O peptídeo sintético idêntico ao C-terminal da proteína S100A9 murina (pS100A9m) possui efeito antinociceptivo em diferentes modelos de dor inflamatória aguda. No presente estudo, o efeito do pS100A9m foi avaliado sobre a dor neuropática induzida pela constrição crônica (CCI) do nervo ciático em ratos. Ainda, foram investigados os possíveis mecani
Publicado em: 2008
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2. Caracterização da atividade antinociceptiva de peptídeos homólogos ao C-terminal da proteína S100A9 murina. Ação sobre neurônios sensoriais via canais de cálcio dependentes de voltagem do tipo N / Characterization of the antinociceptive effect of peptides homologous to the C-terminus of murine S100A9 protein. Effects on sensory neurons, via type-N voltage-dependent calcium channels
O peptídeo idêntico ao C-terminal da proteína S100A9 murina (pS100A9mH92-G110) inibe a hiperalgesia inflamatória induzida pela carragenina. Em adição, este peptídeo inibe a hiperalgesia inflamatória induzida por tripsina, uma serino protease capaz de ativar receptores ativados por protease do tipo 2 (PAR2). O objetivo inicial deste trabalho foi carac
Publicado em: 2006
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3. Organization of early region 1B of human adenovirus type 2: identification of four differentially spliced mRNAs.
The mRNAs from early region 1B of adenovirus type 2 have been studied by Northern blot, S1 nuclease, and cDNA analysis. Two novel mRNAs, designated 14S and 14.5S, have been observed in addition to the previously identified 9S, 13S, and 22S mRNAs. They are 1.26 and 1.31 kilobases long and differ from the 13S and 22S mRNAs in being composed of three exons inst
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4. Activation of multiple antibiotic resistance and binding of stress-inducible promoters by Escherichia coli Rob protein.
Multiple antibiotic resistance in Escherichia coli can be mediated by induction of the SoxS or MarA protein, triggered by oxygen radicals (in the soxRS regulon) or certain antibiotics (in the marRAB regulon), respectively. These small proteins (SoxS, 107 residues; MarA, 127 residues) are homologous to the C terminus of the XylS-AraC family of proteins and ar
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5. Analysis of the Transmembrane Domain of Influenza Virus Neuraminidase, a Type II Transmembrane Glycoprotein, for Apical Sorting and Raft Association
Influenza virus neuraminidase (NA), a type II transmembrane protein, is directly transported to the apical plasma membrane in polarized MDCK cells. Previously, it was shown that the transmembrane domain (TMD) of NA provides a determinant(s) for apical sorting and raft association (A. Kundu, R. T. Avalos, C. M. Sanderson, and D. P. Nayak, J. Virol. 70:6508–
American Society for Microbiology.
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6. Colchicine: A Novel Positive Allosteric Modulator of the Human 5-Hydroxytryptamine3A Receptor
The actions of colchicine were examined with the two-electrode voltage-clamp technique and radioligand binding assays in mouse and human 5-hydroxytryptamine3A receptors (5-HT3ARs) expressed in Xenopus laevis oocytes. Colchicine inhibited 5-hydroxytryptamine (5-HT)-evoked currents in oocytes expressing mouse 5-HT3ARs, with an IC50 of 59.5 ± 3 μM. In co
American Society for Pharmacology and Experimental Therapeutics.
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7. A High-affinity Interaction with ADP-Actin Monomers Underlies the Mechanism and In Vivo Function of Srv2/cyclase-associated ProteinD⃞
Cyclase-associated protein (CAP), also called Srv2 in Saccharomyces cerevisiae, is a conserved actin monomer-binding protein that promotes cofilin-dependent actin turnover in vitro and in vivo. However, little is known about the mechanism underlying this function. Here, we show that S. cerevisiae CAP binds with strong preference to ADP-G-actin (Kd 0.02 μM)
The American Society for Cell Biology.