Carrier Proteins
Mostrando 1-12 de 485 artigos, teses e dissertações.
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1. Synthesis and evaluation of artificial antigens for astragaloside IV
The objective of this study was to produce artificial antigens for astragaloside IV that could be used to prepare antibodies against astragaloside IV screened in Radix astragali (Astragalus membranaceus (Fisch) Bunge, Fabaceae) and its preparations, using an indirect ELISA. Astragaloside IV was coupled to carrier proteins, bovine serum albumin and ovalbumin
Rev. bras. farmacogn.. Publicado em: 2014-06
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2. Hydrogel of polysaccharide of sugarcane molasses as carrier of bone morphogenetic protein in the reconstruction of critical bone defects in rats
PURPOSE: To evaluate the benefit of using carriers such as the biopolymer gel (hidrogel of polysaccharide of sugarcane molasses) associated with the bone morphogenetic proteins (BMP's) in the repair of critical bone defects in calvaria of Wistar rats. METHODS: Forty-two rats were submitted to a surgical calvaria bone defects. These animals were divided into
Acta Cir. Bras.. Publicado em: 2013-04
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3. Influência dos polimorfismos do receptor de leptina e o impacto da dieta e treinamento físico sobre as variáveis antropométricas, metabólicas e neurovasculares em mulheres obesas / Influence of leptin polymorphisms and the impact f diet and exercise training on the anthropometric, metabolic, neurovascular and hemodynamic variables in obese women
Leptin is an important component of a complex physiological system that contributes to the regulation of the organic energy balance. Leptin plasmatic concentration or mRNA quantities are positive related to gender, caloric intake, BMI and fat mass. Energy expenditure can be altered by leptin action through the nervous sympathetic stimulus. Leptin acts via it
Publicado em: 2011
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4. The Na+/glucose cotransporters: from genes to therapy
Glucose enters eukaryotic cells via two types of membrane-associated carrier proteins, the Na+/glucose cotransporters (SGLT) and the facilitative glucose transporters (GLUT). The SGLT family consists of six members. Among them, the SGLT1 and SGLT2 proteins, encoded by the solute carrier genes SLC5A1 and SLC5A2, respectively, are believed to be the most impor
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-11
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5. Osseointegração de implantes em defeitos circunferenciais utilizando proteínas angiogênicas purificadas do látex, osso autógeno e regeneração óssea guiada. Estudo comparativo em mandíbulas de cães / Implant osseointegration in circumferential bone defects using latexderived proteins, autogenous bone graft and guided bone regeneration. A comparative study in the dog mandible
The development of biomaterials that can assist osseointegration and implant stability in dissatisfactory anatomical regions has been the goal of several researches in the past years. Despite the array of regenerative therapies to be used, some clinical disadvantages still persist, such as considerable patient morbidity, extended patient recovery periods, su
Publicado em: 2009
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6. Estudo do perfil de expressão gênica na distrofia muscular fácio-escápulo-umeral (FSH) / Study of gene expression profile in facioscapulohumeral muscular dystrophy (FSHD)
FSHD is characterized by a great clinical inter and intrafamilial variability. Approximately 10-20% of patients eventually becoming wheelchair-bound while 20-30% with a shortened D4Z4 array, remains asymptomatic or minimally affected. Interestingly, these cases seem to be concentrated in some particular families, suggesting that some mechanism might be actin
Publicado em: 2009
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7. Development and evaluation of immunization tools based on the adenovirus fiber knob modified with the C4 domain of HIV gp120 glycoprotein. / Desenvolvimento e avaliação de ferramentas de imunização baseadas na região globular da fibra adenoviral modificada com o domínio C4 da glicoproteína gp120 do HIV.
HIV glycoprotein gp120 has conserved domains, one of them being the C4 domain. This region is involved in the recognition of the CD4 marker in target cells and antibodies that recognize this domain can block HIV infection. Previously, the C4 domain was introduced in the adenovirus fiber knob. As the adenovirus fiber stimulates de immune system, we decided to
Publicado em: 2008
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8. Characterization of chromosome rearrangements in patients with multiple congenital malformation and/or mental retardation (MCM/MR) / Caracterização de rearranjos cromossômicos em pacientes com malformações congênitas múltiplas e/ou retardamento mental (MCA/MR)
Two apparently "de novo" balanced translocations and one duplication of the short arm of chromosome 20 were studied. Our aim was to determine the breakpoints by chromosomal analysis through fluorescentin situ hybridization (FISH) and identify candidate genes and how they were involved with the clinical phenotypes of the patients. Patient 1 carried a duplicat
Publicado em: 2008
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9. Identificação de genes diferencialmente expressos em tomateiro induzidos por ácido salicílico e por Fusarium oxysporum f. sp. lycopersici.
To identify tomato plant (Lycopersicon esculentum Mill), cv. BRH, genes which answer to plant pathogen Fusarium oxysporum f. sp. lycopersici and salicylic acid, the carrier molecule for activation of responses of plant defense, it was used the suppression subtractive hybridization (SSH) technique, from leaf cDNAs, 24h after salicylic acid, library denominate
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 14/06/2007
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10. Emprego do Hamster sírio (Mesocricetus auratus) como modelo biológico para a indução de portador renal de leptospiras / The use of sirius hamster (Mesocricetus Auratus) as a biological model for inducing kidney carrier of leptospirosis
The use of hamsters (Mesocricetus auratus) as experimental model for the reproduction of leptospires kidney carrier condition was investigated on youngs males and females with 80 to 120 g of living weight. The animals were experimentally infected with pathogenic strain of serovar Pomona able of causing the death by leptospirosis between the fifth and the ten
Publicado em: 2006
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11. Clinical, laboratory and epidemiological aspects of naturally acquired Babesia equi infection (Laveran, 1901) in equines from the Academia Militar das Agulhas Negras / Aspectos clínicos, laboratoriais e epidemiológicos da infecção natural por Babesia equi (Laveran, 1901) em eqüinos da Academia Militar das Agulhas Negras
This study was conducted with the purpose to evaluate the clinical, laboratory and epidemiological aspects of naturally acquired Babesia equi infection in 178 horses handled in a semi-intensive system, property of the Academia Militar das Agulhas Negras Brazilian Army, situated in the city of Resende, in the Rio de Janeiro State. Babesia equi is a species of
Publicado em: 2006
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12. Recombinant viruses as vaccines against viral diseases
Vaccine approaches to infectious diseases are widely applied and appreciated. Amongst them, vectors based on recombinant viruses have shown great promise and play an important role in the development of new vaccines. Many viruses have been investigated for their ability to express proteins from foreign pathogens and induce specific immunological responses ag
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-04