Cascade Model
Mostrando 1-12 de 308 artigos, teses e dissertações.
-
1. From yeast to humans: Understanding the biology of DNA Damage Response (DDR) kinases
Abstract The DNA Damage Response (DDR) is a complex network of biological processes that protect cells from accumulating aberrant DNA structures, thereby maintaining genomic stability and, as a consequence, preventing the development of cancer and other diseases. The DDR pathway is coordinated by a signaling cascade mediated by the PI3K-like kinases (PIKK) A
Genet. Mol. Biol.. Publicado em: 13/12/2019
-
2. Bone Marrow Mesenchymal Stem Cells Regulate Coagulation and Inflammation Together in Methotrexate Induced Lung Injury Rat Model
Abstract Clinical research has shed the light on the relation between coagulation and inflammation. Coagulation cascade is activated in lung injury resulting in thrombotic and fibrotic lesions. Such a cascade is initiated by inflammation, then the two systems intense each other. New therapies that modulate coagulation and inflammation will be more successfu
Braz. arch. biol. technol.. Publicado em: 25/11/2019
-
3. Hepatitis C among blood donors: cascade of care and predictors of loss to follow-up
ABSTRACT OBJECTIVE To investigate the HCV cascade of care and to identify the factors associated with loss or absence to follow-up of patients identified as infected with hepatitis C through blood donation. METHODS Blood donors from 1994 to 2012, identified with positive anti- HCV by enzyme immunoassay and immunoblot tests were invited to participate in
Rev. Saúde Pública. Publicado em: 27/04/2017
-
4. Enzyme kinetic modelling and analytical solution of nonlinear rate equation in the transformation of D-methionine into L-methionine in batch reactor using the new homotopy perturbation method
A mathematical model of biotransformation of D-methionine into L-methionine in the cascade of the enzymes such as, D-amino acid oxidase (D-AAO), L-phenylalanine dehydrogenase (L-PheDH) and formate dehydrogenase (FDH) is discussed. The model is based on a system of coupled nonlinear reaction equations under non steady-state conditions for biochemical reaction
Quím. Nova. Publicado em: 2016-12
-
5. ROBUST CONTROL OF WIENER SYSTEMS: APPLICATION TO A pH NEUTRALIZATION PROCESS
Abstract In this paper, the robustness of a typical control scheme for Wiener systems is studied. These systems consist of the cascade connection of a linear time invariant system and a static nonlinearity. To control this kind of systems, several approaches were discussed in the literature. Most of these control schemes involve transformation of the measure
Braz. J. Chem. Eng.. Publicado em: 2016-03
-
6. Effect of hypertonic saline treatment on the inflammatory response after hydrochloric acid-induced lung injury in pigs
OBJECTIVES:Hypertonic saline has been proposed to modulate the inflammatory cascade in certain experimental conditions, including pulmonary inflammation caused by inhaled gastric contents. The present study aimed to assess the potential anti-inflammatory effects of administering a single intravenous dose of 7.5% hypertonic saline in an experimental model of
Clinics. Publicado em: 2015-08
-
7. Effects of Human Umbilical Cord Mesenchymal Stem Cells on Renal Ischaemia-reperfusion Injury in Rats
Objective This study aims to observe the function of umbilical cord-mesenchymal stem cells (UC-MSCs) labelled with enhanced green fluorescent protein (eGFP) in the repair of renal ischaemia-reperfusion (I/R) injury, to determine the effects on inflammatory cascade in an established rat model and to explore possible pathogenesis. Materials and Methods Si
Int. braz j urol.. Publicado em: 2014-08
-
8. Transduction motif analysis of gastric cancer based on a human signaling network
To investigate signal regulation models of gastric cancer, databases and literature were used to construct the signaling network in humans. Topological characteristics of the network were analyzed by CytoScape. After marking gastric cancer-related genes extracted from the CancerResource, GeneRIF, and COSMIC databases, the FANMOD software was used for the min
Braz J Med Biol Res. Publicado em: 04/04/2014
-
9. Multistage axial-flow turbines : design and performance analysis
Plans for developing turbines in Brazil were present on the conception of CTA six decades ago. In this manner highly specialized work teams is needed to carry out such activity. The Center for Reference on Gas Turbine group has been contributing to research activities at CTA taking account of the study of gas turbines both aeronautical and industrial. In ord
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/06/2012
-
10. The Hirschsprung's-multiple endocrine neoplasia connection
The risk of patients with Hirschsprung's disease later developing multiple endocrine neoplasia remains a matter of concern. The multiple endocrine neoplasia 2-Hirschsprung's disease association has been shown to cosegregate in Hirschsprung's disease patients with both short- and long-segment aganglionosis, although patients with long-segment aganglionosis a
Clinics. Publicado em: 2012
-
11. Papel de TGFβ-1 na regulação da expressão de MMPs seus inibidores (TIMPs e Reck) em modelo de carcinoma mamário humano: análise funcional de RECK e sua correlação com dados clínico-patológicos / Role of TGFβ-1 as a common regulator of MMPs and their inhibitors (TIMPs e RECK) in human breast cancer cell model: functional analysis of RECK and its correlation with clinical-pathological
The metastatic disease is the main mortality cause of breast cancer patients. The metastatic process involves a complex cascade of events, including the organized breakdown of the extracellular matrix (ECM) compounds. The degradation of ECM is tightly regulated by the balance between the activities of matrix metalloproteinases (MMPs) and their inhibitors, th
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 14/10/2011
-
12. EIXO ECA2/ANG-(1-7)/MAS E SUA REGULAÇÃO NO PROCESSO DE OVULAÇÃO / ECA2/ANG-(1-7)/MAS AXIS AND ITS REGULATION DURING THE PROCESS OF OVULATION
The Renin-Angiotensin System (RAS) has been associated with various reproductive functions, including the ovulatory cascade. Unlike angiotensin II (AngII), the role of angiotensin-(1-7) [Ang-(1-7)] has not been characterized in the ovary of mono-ovulatory species. The objective of this study was to determine the Ang-(1-7) concentration in follicular fluid an
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/02/2011